Olfr918 Activators
Olfr918, an olfactory receptor protein, is a crucial component of the olfactory system's ability to discern a wide range of odorant molecules. As part of the G-protein coupled receptors (GPCRs) family, it plays a vital role in the transduction of chemical signals from the external environment into neural signals, a process fundamental to the perception of scents. The functional activation of Olfr918, as with other olfactory receptors, is initiated upon the binding of specific odorant molecules. This binding results in a conformational change in the receptor, which is key to starting the signal transduction pathway. The interaction between Olfr918 and these odorant molecules is highly specific and dependent on the structural compatibility between the two. This specificity is critical for the selective detection and differentiation of odors. Compounds such as octyl acetate, benzyl acetate, and ethyl hexanoate, when bound to Olfr918, induce structural changes that trigger the activation of associated G-proteins. This activation leads to a cascade of intracellular signaling events, including the production of secondary messengers like cyclic AMP and an increase in intracellular calcium levels. These messengers play a pivotal role in amplifying the olfactory signal, leading to a neural response. This precise mechanism of activation allows the olfactory system to accurately perceive a wide array of odors, demonstrating the complexity and efficiency of the system.
Moreover, the ability of Olfr918 to be activated by various chemicals with distinct structural features underlines the broad specificity of olfactory receptors. This characteristic enables the olfactory system to detect and process a wide variety of odorant molecules, each imparting a unique sensory experience. The exact interaction of these chemicals with Olfr918 is essential for the accurate functioning of the olfactory system, facilitating the detection and perception of odors. This interaction is fundamental to our sense of smell, significantly impacting our daily life and interactions with the environment, and contributing to our overall quality of life.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Octyl acetate | 112-14-1 | sc-236244 | 5 g | $24.00 | ||
Octyl acetate activates Olfr918 by binding to its olfactory receptor sites, inducing a conformational change in the protein. This interaction triggers the activation of G-protein coupled signaling pathways, leading to increased intracellular calcium levels and cyclic AMP, essential for the functional activation and signal transduction of Olfr918, enhancing the perception of its fruity and floral odor. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $30.00 | 1 | |
Benzyl acetate, with its sweet floral aroma, activates Olfr918 through binding to its specific olfactory receptor sites. This binding induces a structural alteration in Olfr918, initiating the activation of G-protein coupled intracellular signaling pathways. These pathways, particularly those involving the elevation of cyclic AMP, are crucial for the functional activation of Olfr918, facilitating olfactory signal transmission. | ||||||
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $51.00 | ||
Ethyl hexanoate activates Olfr918 by interacting with its olfactory binding sites. This interaction results in a conformational change in Olfr918, leading to the activation of downstream G-protein coupled pathways. The activation of these pathways, especially those that increase cyclic AMP levels, is essential for the functional activation and signal transduction of the olfactory receptor Olfr918. | ||||||
Methyl benzoate | 93-58-3 | sc-215338 sc-215338A | 25 g 500 g | $23.00 $33.00 | ||
Methyl benzoate, known for its sweet and balsamic scent, activates Olfr918 by binding to its olfactory receptor sites. This binding triggers a change in the receptor's conformation, activating associated G-protein coupled signaling pathways. These pathways, including the rise in intracellular calcium and cyclic AMP levels, are crucial for the functional activation and proper signal transduction of Olfr918. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates Olfr918 by binding to its olfactory receptor sites, causing a conformational change in the receptor. This change facilitates the activation of G-protein coupled pathways, resulting in intracellular signaling events. The increase in cyclic AMP, particularly, is essential for the functional activation of Olfr918, playing a key role in the perception of ethyl butyrate's fruity odor. | ||||||
Butyl butyrate | 109-21-7 | sc-239439 | 250 ml | $210.00 | ||
Butyl butyrate, a compound with a fruity and buttery odor, activates Olfr918 by interacting with its specific olfactory receptor binding sites. This interaction causes a change in the receptor's structure, triggering the activation of G-protein coupled signal transduction pathways. The activation of these pathways, especially those involving cAMP, is vital for the functional activation of Olfr918, enhancing the perception of its scent. | ||||||
Ethyl valerate | 539-82-2 | sc-215002 | 500 ml | $83.00 | ||
Ethyl valerate activates Olfr918 through molecular binding at its specific olfactory receptor sites. This binding induces a conformational change in Olfr918, leading to the activation of downstream G-protein coupled pathways. These pathways are essential for the transduction of olfactory signals mediated by Olfr918, particularly the increase in cyclic AMP levels. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate, known for its banana-like aroma, activates Olfr918 by binding to its olfactory receptor sites. This interaction induces a structural alteration in Olfr918, leading to the activation of G-protein coupled intracellular signaling pathways. The activation of these pathways, especially those resulting in the increase of intracellular calcium levels, is crucial for the functional activation of Olfr918. | ||||||
n-Propyl hexanoate | 626-77-7 | sc-281095 sc-281095A sc-281095B | 25 g 100 g 500 g | $87.00 $280.00 $602.00 | ||
Propyl hexanoate, with its fruity and slightly woody aroma, activates Olfr918 by interacting with its specific olfactory receptor sites. This binding induces a structural change in Olfr918, triggering the activation of G-protein coupled signaling pathways. The activation of these pathways, including increased intracellular calcium levels, is vital for the functional activation of the olfactory receptor Olfr918. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate activates Olfr918 through binding to its olfactory receptor sites. This interaction induces a conformational change in the receptor, leading to the activation of G-protein coupled pathways. The subsequent intracellular signaling cascade, particularly the rise of cyclic AMP, is essential for the functional activation of Olfr918, contributing to the perception of its wintergreen aroma. | ||||||