Olfr90 Activators
Olfr90 is an olfactory receptor protein responsible for detecting specific odorants in our environment. Its activation is crucial for our sense of smell. Olfr90 directly recognizes and responds to odorant molecules by binding to its receptor site, initiating a conformational change. This change triggers olfactory signal transduction, leading to the functional activation of Olfr90. In addition to direct activation, Olfr90 can also be indirectly activated by chemicals like Adenosine Triphosphate (ATP) and Inositol Trisphosphate (IP3). These compounds enhance olfactory receptor sensitivity by modulating intracellular calcium levels, which amplifies Olfr90's responsiveness to odorants. Similarly, chemicals like 2-Aminoethoxydiphenyl Borate and Guanosine Triphosphate (GTP) influence G-protein coupled signaling pathways, leading to increased sensitivity of olfactory receptors, including Olfr90, to odorants.
In summary, Olfr90 is a vital component of our olfactory system, allowing us to perceive and distinguish various scents in our environment. Its activation is achieved through direct binding to odorants or indirectly by modulating intracellular pathways that enhance receptor sensitivity, ultimately leading to our ability to detect and recognize specific smells.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $39.00 $68.00 | ||
Menthol directly activates Olfr90 by binding to its receptor site, inducing a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr90. | ||||||
1,8-Cineole | 470-82-6 | sc-485261 | 25 ml | $44.00 | 2 | |
1,8-Cineole directly activates Olfr90 by binding to its receptor site, leading to a conformational change that triggers olfactory signal transduction, ultimately resulting in the functional activation of Olfr90. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral directly activates Olfr90 by binding to its receptor site, inducing a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr90. | ||||||
(+)-Carvone | 2244-16-8 | sc-239480 sc-239480A | 5 ml 25 ml | $33.00 $84.00 | 2 | |
Carvone directly activates Olfr90 by binding to its receptor site, initiating a conformational change that triggers olfactory signal transduction, leading to the functional activation of Olfr90. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool directly activates Olfr90 by binding to its receptor site, leading to a conformational change that initiates olfactory signal transduction, ultimately resulting in the functional activation of Olfr90. | ||||||
ATP | 56-65-5 | sc-507511 | 5 g | $17.00 | ||
Adenosine Triphosphate (ATP) indirectly activates Olfr90 by increasing intracellular calcium levels, which enhances the sensitivity of olfactory receptors, including Olfr90, to odorant molecules. This leads to functional activation of Olfr90 in the detection of specific scents. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $28.00 $53.00 | 37 | |
2-Aminoethoxydiphenyl Borate indirectly activates Olfr90 by modulating the olfactory signal transduction pathway. It enhances the production of inositol trisphosphate (IP3), leading to increased intracellular calcium levels, which in turn amplifies the sensitivity of olfactory receptors, including Olfr90, to odorants. This promotes their functional activation in odor detection. | ||||||
Guanosine 5′-Triphosphate, Disodium Salt | 56001-37-7 | sc-295030 sc-295030A | 50 mg 250 mg | $166.00 $327.00 | ||
Guanosine Triphosphate (GTP) indirectly activates Olfr90 by influencing G-protein coupled signaling pathways. It activates G-proteins, leading to the generation of second messengers like cyclic AMP (cAMP) and IP3. This modulation enhances the sensitivity of olfactory receptors, including Olfr90, to odorants, facilitating their functional activation in odor detection. | ||||||