Olfr819 Activators
Olfr819 Activators, a diverse group of chemical compounds, play a significant role in modulating the functional activity of Olfr819, a key player in olfactory perception. Forskolin and IBMX stand out for their ability to manipulate cAMP levels within olfactory sensory neurons, a critical factor for cyclic nucleotide-gated ion channels' functioning, which are integral to Olfr819's signaling pathway. Zinc Sulfate and Sodium Cyclamate further contribute by modulating enzyme activities and altering intracellular environments, respectively, thereby enhancing Olfr819's sensitivity and response to odorants. Additionally, Bicyclo[2.2.1]heptane derivatives and Cinnamaldehyde, through their influence on neuronal membrane dynamics and intracellular signaling, could indirectly enhance Olfr819's conformational flexibility and interaction with specific odorants.
Furthering this intricate modulation, Capsaicin and Menthol impact sensory neuron signaling, potentially affecting Olfr819's activity by modifying membrane properties or intracellular pathways. Ethanol and Diethyl Ether, by altering neuronal membrane fluidity and signaling, could lead to enhanced odorant binding or signal transduction efficiency of Olfr819. Lastly, Citral and Eugenol, through their interactions with neuronal signaling pathways, indirectly augment Olfr819's functional activity. These activators, by affecting various aspects of neuronal dynamics and signaling pathways, collectively enhance the sensitivity and efficiency of Olfr819 in olfactory transduction, thereby playing a crucial role in the nuanced processes of olfactory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Stimulates adenylyl cyclase, increasing cAMP levels in olfactory sensory neurons. Elevated cAMP enhances Olfr819's signal transduction by facilitating the opening of cyclic nucleotide-gated ion channels in the olfactory pathway. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Acts as a non-selective phosphodiesterase inhibitor, maintaining high cAMP levels. This supports Olfr819 activation by sustaining cAMP signaling, crucial for cyclic nucleotide-gated channels in olfactory transduction. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Influences olfactory signaling. Zinc ions modulate the activity of enzymes and ion channels in the pathway, potentially enhancing Olfr819's sensitivity and response in olfactory neurons. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Alters intracellular signaling pathways in olfactory neurons. It may enhance Olfr819 activation by modifying the receptor's ability to bind to specific odorants or by altering intracellular signal transduction pathways. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Influences sensory neuron signaling. It could enhance Olfr819's activity by modulating neuronal membrane properties or intracellular signaling pathways, thereby affecting the receptor's odorant binding or signal transduction. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $38.00 $67.00 | ||
Modulates ion channels in sensory neurons. This can indirectly enhance Olfr819's functionality by altering neuronal excitability or signal transduction pathways involved in olfactory perception. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Interacts with sensory neuron signaling. It may indirectly augment Olfr819's activity by affecting its odorant binding capabilities or the efficiency of intracellular signal transduction mechanisms. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Influences neuronal signaling pathways. This can indirectly enhance Olfr819's activity by modifying receptor dynamics, membrane properties, or intracellular signaling processes in olfactory neurons. | ||||||