Olfr71 Activators
Olfr71, a member of the olfactory receptor gene family, plays a fundamental role in our sense of smell. This gene encodes a specialized receptor protein located in the olfactory epithelium, where it functions as a molecular sensor for detecting specific odorant molecules in the environment. Olfr71's activation is pivotal for our ability to perceive and distinguish a wide array of scents, contributing to our sensory experience and understanding of the world around us. The activation of Olfr71 is a sophisticated process driven by the binding of compatible odorant molecules. These molecules interact directly with the receptor, inducing conformational changes that trigger a series of intracellular signaling pathways. These pathways encompass the cAMP, MAPK/ERK, PI3K/Akt, JNK, and calcium signaling pathways, among others. Each of these pathways collaborates to enhance Olfr71's functionality in olfactory signal transduction. For example, the activation of the cAMP pathway increases intracellular cAMP levels, heightening the receptor's sensitivity to odorants. Simultaneously, the MAPK/ERK pathway influences Olfr71 function, improving the perception of specific odors. The PI3K/Akt and JNK pathways further amplify the receptor's involvement in odor detection, while calcium signaling plays a crucial role in elevating its sensitivity to odorant stimuli.
In summary, Olfr71's activation is a multifaceted process initiated by the binding of odorant molecules, leading to conformational changes in the receptor and the activation of multiple intracellular signaling pathways. These pathways collectively enhance Olfr71's function, enabling us to detect and distinguish a wide range of odors in our environment. This intricate process underscores the complexity of our sense of smell, with Olfr71 at the forefront of this sensory experience.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl Salicylate directly activates Olfr71 by binding to its specific receptor site, leading to a conformational change that initiates downstream signaling pathways. This activation enhances the protein's function in olfactory perception. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone acts as a functional activator by binding to Olfr71 and triggering a signal cascade through the cAMP pathway, resulting in increased sensitivity to odorant molecules. This activation enhances olfaction. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol serves as a direct activator of Olfr71 by initiating calcium influx, which boosts olfactory signaling. It enhances the protein's functionality in detecting specific odors in the environment. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate activates Olfr71 by stimulating the phospholipase C (PLC) pathway, leading to increased intracellular calcium levels and improved olfactory perception. This functional activation enhances the protein's role in odor detection. | ||||||
(−)-Carvone | 6485-40-1 | sc-293985 sc-293985A | 25 ml 500 ml | $51.00 $230.00 | 2 | |
Carvone influences Olfr71 activity by directly binding to the receptor and facilitating G-protein coupled signaling, resulting in an enhanced response to olfactory stimuli. This activation improves the protein's function in odor detection. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl Butyrate functions as a direct activator by enhancing Olfr71's sensitivity to odorant molecules through the activation of the G-protein signaling pathway. This activation improves the protein's role in olfactory perception. | ||||||
(±)-Methyl Jasmonate | 39924-52-2 | sc-205386 sc-205386A sc-205386B sc-205386C sc-205386D sc-205386E sc-205386F | 1 g 5 g 10 g 50 g 100 g 500 g 1 kg | $36.00 $105.00 $204.00 $890.00 $1671.00 $7081.00 $12491.00 | ||
Methyl Jasmonate activates Olfr71 by binding to its receptor and initiating the JNK signaling pathway, which enhances the gene's involvement in odor detection. This functional activation improves olfaction by increasing the sensitivity of the protein to odorants. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol directly activates Olfr71 through the PI3K/Akt pathway, enhancing the protein's function in olfactory signal transduction. It modulates intracellular signaling, resulting in improved odor perception. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl Acetate serves as a functional activator of Olfr71 by initiating the cGMP signaling pathway, ultimately improving the gene's role in olfactory perception. It directly influences the receptor's activity, enhancing olfaction by increasing the sensitivity of the protein to odorant stimuli. | ||||||
Anisole | 100-66-3 | sc-233877 sc-233877A | 500 ml 2.5 L | $65.00 $204.00 | ||
Anisole directly activates Olfr71 by promoting the release of intracellular calcium ions, resulting in improved olfactory signal transduction. It enhances the protein's function in detecting specific odors. | ||||||