Olfr69 Activators
Olfr69 is a gene that encodes an olfactory receptor, part of the extensive family of G-protein-coupled receptors (GPCRs). These receptors are crucial in the olfactory system, enabling organisms to detect and differentiate a myriad of odors. The protein product of Olfr69 is primarily found in the olfactory epithelium, the sensory tissue in the nose responsible for odor detection. Olfactory receptors like Olfr69 play a pivotal role in converting chemical signals from odor molecules into electrical signals that the brain interprets as distinct smells. This process is essential for various physiological and behavioral responses, including food selection, danger recognition, and social communication. The activation of Olfr69, as with other olfactory receptors, occurs when specific odorant molecules bind to the receptor. This binding is highly selective, with certain chemical structures fitting into the receptor in a manner akin to a key fitting into a lock. Upon the binding of an odorant, Olfr69 undergoes a conformational change, marking the initial step in the receptor's activation. This activation then triggers interactions with an intracellular G-protein, leading to a series of biochemical reactions. The G-protein, upon activation, undergoes a change involving the exchange of GDP for GTP on its alpha subunit, which in turn activates further signaling pathways within the cell. These pathways culminate in the generation of an electrical signal that is transmitted to the brain and perceived as a specific odor.
Each olfactory receptor, including Olfr69, is capable of binding to multiple related chemical compounds, allowing the olfactory system to detect and distinguish a vast array of odors. This ability to discriminate among different odors is a hallmark of the olfactory system and is critical for survival and reproduction in many species. Understanding the activation and function of olfactory receptors such as Olfr69 is not only fundamental to our knowledge of sensory biology but also has potential applications in various fields. These include the development of artificial noses for environmental monitoring, the creation of novel fragrances and flavors, and potentially even in medical diagnostics. The study of olfactory receptors, their activation mechanisms, and their interactions with odorants provides valuable insights into the complex and nuanced nature of smell, a sense that is integral to our experience of the world.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate can activate Olfr69 by binding to its specific olfactory receptor site, triggering a conformational change in the receptor. This change leads to the activation of associated G-proteins and the initiation of olfactory signal transduction pathways. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, through its interaction with Olfr69, can activate the receptor by directly binding to it. This binding induces a conformational change in Olfr69, enabling the activation of G-protein signaling pathways integral to the olfactory signal transduction process. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate can activate Olfr69 by binding to the receptor's specific site. This interaction triggers a conformational alteration in Olfr69, facilitating the activation of downstream G-protein mediated signaling mechanisms involved in olfactory perception. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl salicylate can activate Olfr69 by interacting with its sensory domain. This binding facilitates the activation of the receptor, promoting the initiation of G-protein coupled intracellular signaling pathways involved in the perception of olfactory cues. | ||||||
Benzyl alcohol | 100-51-6 | sc-326216B sc-326216 sc-326216A | 250 ml 1 L 5 L | $31.00 $102.00 $408.00 | ||
Benzyl alcohol can activate Olfr69 through its interaction with the receptor's binding site. This binding promotes a change in receptor conformation, enabling the activation of associated G-protein signaling pathways, critical for olfactory signal transduction. | ||||||
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $50.00 | ||
Ethyl hexanoate can activate Olfr69 by binding to its ligand-specific site. This interaction induces a receptor conformational change, leading to the activation of G-protein mediated signaling pathways involved in olfactory perception. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, by interacting with Olfr69, can activate the receptor through direct binding. This interaction induces a conformational change, leading to the activation of G-protein signaling pathways integral to the olfactory signal transduction process. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $46.00 $71.00 $108.00 | ||
Linalool can activate Olfr69 through binding to the receptor's specific site. This interaction triggers a conformational alteration of Olfr69, facilitating the activation of downstream G-protein mediated signaling mechanisms involved in olfactory perception. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $68.00 | ||
2-Phenylethanol can activate Olfr69 by binding to its sensory domain. This binding facilitates the activation of the receptor, promoting the initiation of G-protein coupled intracellular signaling pathways involved in the perception of olfactory cues. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $51.00 $113.00 | 2 | |
Alpha-Pinene can activate Olfr69 through its interaction with the receptor's binding site. This binding promotes a change in receptor conformation, enabling the activation of associated G-protein signaling pathways, critical for olfactory signal transduction. | ||||||