Olfr681 Activators
Olfr681 is an olfactory receptor gene, one of many that contribute to the intricate and highly specialized sense of smell in mammals. The protein encoded by this gene, also referred to as Olfr681, is a G-protein-coupled receptor (GPCR) located in the olfactory epithelium. The primary function of Olfr681, like other olfactory receptors, is to detect volatile chemical compounds in the external environment and transduce this information into a neuronal signal that can be processed by the brain, ultimately contributing to the perception of smell.
The mechanism of activation for Olfr681, as with most olfactory receptors, involves the binding of specific odorant molecules to the receptor, which induces a conformational change in the receptor's structure. This change is critical as it initiates the activation of the receptor. Upon activation, Olfr681 interacts with a G-protein, leading to the exchange of GDP for GTP on the G-protein's alpha subunit. This exchange triggers the dissociation of the G-protein into its alpha and beta-gamma subunits. The subunits then interact with downstream effectors, leading to a cascade of intracellular events that ultimately result in an electrical signal being sent to the brain. This process, known as signal transduction, is fundamental to how olfactory receptors, including Olfr681, convey information about the presence of odorant molecules. The specificity of odorant-receptor interactions is a hallmark of the olfactory system, allowing for the detection and discrimination of a vast array of distinct odors. Each olfactory receptor, including Olfr681, typically binds to multiple related odorant molecules, contributing to the combinatorial nature of olfactory perception. This characteristic allows for the detection of a wide variety of smells from a limited number of receptors. Olfr681's role in this complex system underscores the importance of molecular diversity and specificity in the olfactory process.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone, being a small aromatic ketone, can interact with the binding site of Olfr681, leading to a conformational change that activates the receptor. This activation may trigger downstream signaling cascades associated with olfactory reception. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate, often recognized for its banana-like odor, can bind to the sensory domain of Olfr681, activating the receptor. This binding can initiate a G-protein coupled reaction, leading to signal transduction mechanisms relevant to olfactory processes. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin, a phenolic aldehyde, can bind to and activate Olfr681. This activation potentially involves the interaction with key amino acids in the receptor's binding site, leading to a change in receptor conformation and subsequent activation of G-protein mediated olfactory signaling pathways. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, a fruity smelling ester, can activate Olfr681 through binding to its ligand-binding site. This interaction promotes a conformational change in the receptor, enabling it to activate associated G-proteins, which then propagate the olfactory signal. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate, known for its wintergreen scent, can activate Olfr681 by binding to its sensory domain. This binding facilitates receptor activation, promoting the initiation of intracellular signaling pathways involved in the perception of olfactory cues. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, a component of clove oil, can activate Olfr681 by interacting with the receptor's binding site. This interaction induces a change in the receptor's conformation, triggering the activation of downstream G-protein coupled pathways relevant to olfactory signaling. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamic Aldehyde, recognizable for its cinnamon aroma, can activate Olfr681 through its binding to the receptor. This interaction leads to receptor activation, thereby facilitating the initiation of signal transduction mechanisms associated with the sense of smell. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene, a citrus-scented compound, can activate Olfr681 by binding to its ligand-specific site. This binding induces a receptor conformational change, leading to the activation of G-protein mediated signaling pathways involved in olfactory perception. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole, a compound with a licorice-like aroma, can activate Olfr681 by interacting with its binding domain. This interaction causes a conformational shift in the receptor, enabling it to activate downstream signaling pathways integral to olfactory reception. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, with its rose-like scent, can activate Olfr681 by binding to the receptor's sensory domain. This binding facilitates receptor activation and the subsequent initiation of G-protein coupled intracellular signaling mechanisms relevant to the detection of olfactory stimuli. | ||||||