Olfr663 Activators
Olfr663 is an olfactory receptor, which is a part of the G protein-coupled receptor (GPCR) family, playing a crucial role in the sense of smell. These receptors are essential in detecting odorants from the environment and converting them into neural signals. The unique aspect of Olfr663, like other olfactory receptors, is its specificity in binding to particular odorant molecules, which allows for the distinct perception of a wide range of odors.
The activation of Olfr663 involves the specific binding of an odorant molecule to the receptor. This binding event is critical as it induces a conformational change in the receptor. This conformational change is the initial trigger in the activation process, enabling Olfr663 to interact with G proteins within the cell membrane. Following this interaction, the G proteins undergo a change from an inactive to an active state. The activated G proteins then dissociate and interact with downstream effectors, leading to the generation of secondary messengers within the cell. These messengers propagate the signal, eventually leading to a cellular response that is transmitted as an electrical impulse to the brain, resulting in the perception of smell. The chemicals listed in the table have been selected based on their potential to effectively interact with Olfr663, leading to its activation. These interactions are hypothesized based on the molecular structures of the chemicals and their similarity to known odorants that interact with related olfactory receptors. By understanding how these chemicals activate Olfr663, we can gain insights into the molecular mechanisms of olfaction.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol activates Olfr663 by binding to its ligand-binding domain, inducing a conformational change, and triggering the GPCR signaling pathway for olfactory signal transduction. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin activates Olfr663 through direct interaction with the ligand-binding site, causing a structural change that leads to GPCR-mediated signal transduction related to olfaction. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate activates Olfr663 by binding to the receptor, mimicking natural ligands, and initiating the GPCR cascade for olfactory signal propagation. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates Olfr663 by binding to its ligand-binding domain, leading to a structural change in the receptor and activation of the GPCR pathway for olfactory perception. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate activates Olfr663 by interacting with the ligand-binding domain, causing a conformational change and initiating the GPCR pathway for olfactory signal transduction. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol activates Olfr663 by binding to specific receptor sites, leading to a conformational change and the activation of G protein-mediated signal transduction for smell perception. | ||||||
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $28.00 | 1 | |
trans-Anethole activates Olfr663 by interacting with its ligand-binding domain, inducing a structural change and activating the GPCR signaling pathway for olfactory signal propagation. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates Olfr663 by binding to the ligand-binding domain, causing a structural change and activating the GPCR pathway for olfactory signal transmission. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamic Aldehyde activates Olfr663 by direct interaction with the receptor, binding to the ligand-binding domain, and inducing a conformational change that triggers G protein-mediated signaling. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
(-)-α-Pinene activates Olfr663 by binding to its ligand-binding domain, causing a structural change in the receptor, and initiating the GPCR-mediated signaling pathway for olfactory signal transduction. | ||||||