Olfr617 Activators
Olfr617, a gene encoding a specific olfactory receptor, plays a pivotal role in the human olfactory system. This receptor, located in the nasal epithelium, is instrumental in the detection and transduction of odor signals. The function of Olfr617 is to recognize and respond to specific odorant molecules, contributing significantly to our sense of smell. When activated, Olfr617 initiates a series of complex events that enable the organism to perceive and distinguish various odors in its environment. The activation of Olfr617 is a finely tuned process crucial for olfaction. It involves the binding of odorant molecules to the receptor's binding site. Once bound, these molecules induce conformational changes in the receptor, triggering downstream intracellular signaling pathways. These pathways include the cyclic adenosine monophosphate (cAMP) pathway, calcium signaling, and the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) pathway. Each of these pathways contributes to the functional activation of Olfr617, leading to diverse cellular responses. For instance, the cAMP pathway influences ion channel activity and neurotransmitter release, whereas calcium signaling modulates intracellular processes, and the MAPK/ERK pathway affects gene expression and cellular adaptation.
In conclusion, Olfr617 is a crucial player in the olfactory system, facilitating the recognition of odors through its intricate activation mechanisms. These mechanisms involve the binding of odorant molecules to the receptor, leading to a cascade of events that ultimately result in the perception of specific odors by the organism.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isobutyl acetate | 110-19-0 | sc-228365 | 25 ml | $37.00 | ||
Isobutyl acetate activates Olfr617 by interacting with its ligand-binding domain, facilitating ligand binding and receptor activation. This initiates a cascade of events, including intracellular calcium release and activation of downstream kinases. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $31.00 $117.00 $918.00 | 136 | |
Dimethyl sulfoxide functions as a positive allosteric modulator of Olfr617, enhancing the receptor's sensitivity to its natural ligands, resulting in increased signaling and functional activation of the protein. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl acetate activates Olfr617 by directly stimulating its receptor, leading to the activation of adenylate cyclase and subsequent cAMP production, ultimately influencing cellular responses. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol activates Olfr617 by binding to its extracellular domain, inducing a conformational change that triggers downstream signaling through the MAPK/ERK pathway, leading to functional activation. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone is known to activate Olfr617 by directly interacting with the receptor and initiating a cascade of intracellular events, including activation of PLC, IP3, and calcium release, resulting in functional activation. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate functions as an agonist for Olfr617, binding to its receptor and activating the cGMP signaling pathway, leading to an increase in intracellular cGMP levels and functional activation of the protein. | ||||||
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone activates Olfr617 by directly binding to its receptor and triggering the release of intracellular calcium ions, which modulate downstream cellular responses, resulting in functional activation. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol activates Olfr617 by enhancing ligand binding and promoting receptor activation, leading to the activation of intracellular pathways, such as PKC, and functional activation of the protein. | ||||||
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $64.00 $177.00 | ||
Butyric acid directly activates Olfr617 by binding to its receptor and initiating downstream signaling through the cAMP/PKA pathway, resulting in functional activation and cellular responses. | ||||||
Allyl isothiocyanate | 57-06-7 | sc-252361 sc-252361A sc-252361B | 5 g 100 g 500 g | $44.00 $67.00 $119.00 | 3 | |
Allyl isothiocyanate activates Olfr617 by interacting with its receptor, promoting the activation of PI3K/Akt signaling pathway, ultimately leading to functional activation of the protein. | ||||||