Olfr597 Activators
Olfr597, as a member of the olfactory receptor family, plays a crucial role in the detection and differentiation of odorous compounds. These receptors, classified under the G-protein-coupled receptor (GPCR) superfamily, are vital in the process of olfaction, translating chemical signals into neural responses. The functional activation of Olfr597 is central to this sensory process, facilitating the recognition and interpretation of a wide array of scents. The activation mechanism of Olfr597 involves the direct interaction of specific chemical ligands with the receptor. This binding is highly selective, ensuring the activation of Olfr597 by particular odorant molecules. Upon ligand binding, Olfr597 undergoes a significant conformational change, marking the initiation of its activation. This structural alteration is pivotal for the activation of the associated G-protein, typically G_olf in olfactory neurons. The process includes the exchange of GDP for GTP on the G_α subunit of the G-protein, followed by its dissociation from the G_βγ dimer. The dissociated G_α subunit then activates adenylate cyclase III, catalyzing the conversion of ATP to cyclic AMP (cAMP). The increase in cAMP levels opens cyclic nucleotide-gated ion channels, permitting the influx of calcium and sodium ions. This ion movement generates an electrical signal that is conveyed to the brain, resulting in the perception of a distinct odor.
The activation of Olfr597 by various chemical activators highlights the accuracy and complexity of the olfactory system. This specificity in ligand-receptor interaction is essential for the precise detection and differentiation of odors, illustrating the intricate relationship between chemical compounds and biological receptors. The olfactory perception process, exemplified by Olfr597's activation, demonstrates the advanced biological mechanisms underlying sensory systems. The direct activation of Olfr597 by these odorant molecules underscores its role in olfactory perception and provides insights into the broader principles of receptor-ligand interactions within biological systems.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates Olfr597 by directly binding to its specific odorant-binding site, inducing a conformational change essential for receptor activation. This interaction triggers G-protein signaling pathways, crucial for olfactory signal transduction. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate engages Olfr597 by interacting with its ligand-binding domain, causing a structural change in the receptor and activating it. This leads to the initiation of G-protein coupled signaling pathways essential for olfactory perception. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool activates Olfr597 through direct binding to its odorant receptor site, causing a conformational alteration and subsequent activation of the receptor. This initiates G-protein signaling cascades vital for olfactory perception. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol binds to Olfr597, inducing a structural change that activates the receptor. This activation facilitates the propagation of signal transduction pathways linked to olfactory receptor activation. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $30.00 | 1 | |
Benzyl acetate directly binds to Olfr597, resulting in receptor activation. This interaction triggers a series of G-protein mediated signaling events, fundamental to the function of olfactory receptors in scent detection. | ||||||
Geranyl acetate | 105-87-3 | sc-235243 | 25 g | $41.00 | ||
Geranyl acetate interacts with Olfr597 at its odorant-binding site, activating the receptor. This activation triggers G-protein mediated signaling pathways, essential for the transduction of olfactory signals. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate activates Olfr597 by binding to its ligand-specific site, causing a conformational change and initiating the activation of G-protein signaling mechanisms important for olfactory processing. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate, by binding to Olfr597, activates the receptor and initiates a series of G-protein mediated signaling events, crucial for olfactory signal detection and interpretation. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
3-Ethoxy-4-hydroxybenzaldehyde activates Olfr597 through direct ligand-receptor interaction, inducing a structural alteration essential for receptor activation and triggering G-protein signaling pathways involved in olfactory signal processing. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamic Aldehyde binds to Olfr597, causing receptor activation through a structural change. This activation leads to the initiation of G-protein mediated signaling pathways, essential for the perception of specific odors. | ||||||