Olfr578 Activators
Olfr578, a member of the olfactory receptor gene family, plays a crucial role in the intricate process of olfaction, which is the sense of smell. Located within the olfactory sensory neurons of the nasal epithelium, Olfr578 is specialized in detecting specific odor molecules and transducing these signals into neural responses. In the highly organized and diverse olfactory system, Olfr578 is finely tuned to recognize distinct chemical compounds, contributing to our ability to perceive a wide range of odors in the environment.
The activation of Olfr578 is a finely orchestrated process that involves its interaction with various chemical compounds. When odorant molecules, such as those listed in the previous table, come into contact with Olfr578, they bind to specific receptor sites on the olfactory sensory neurons. This binding event initiates a cascade of intracellular events, starting with the activation of adenylate cyclase. This enzyme catalyzes the conversion of adenosine triphosphate (ATP) into cyclic adenosine monophosphate (cAMP), leading to an increase in intracellular cAMP levels. Elevated cAMP levels, in turn, trigger the activation of protein kinase A (PKA). PKA then phosphorylates Olfr578, resulting in its functional activation. The recognition and activation of Olfr578 by these odorant compounds are highly specific, with each chemical interacting uniquely with the receptor's binding site. This specificity allows Olfr578 to distinguish between various odors, and the resulting neural signals are transmitted to the brain, where they are decoded, leading to the perception of distinct olfactory sensations. Overall, Olfr578's role in the olfactory system is pivotal in our ability to detect and identify a wide array of odors in our surroundings, contributing to the richness of our sensory experiences.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates Olfr578 by directly stimulating adenylate cyclase, which leads to an increase in intracellular cAMP levels. Elevated cAMP levels activate protein kinase A (PKA), which, in turn, phosphorylates and activates Olfr578, enhancing its function in the olfactory signaling pathway. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate activates Olfr578 by binding to its odorant binding site, inducing a conformational change that triggers downstream signaling events. This chemical specifically activates the olfactory receptor, leading to an odor perception response. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone functions as an activator of Olfr578 by binding to its receptor site, initiating a signal transduction cascade. This activation results in the perception of specific odors associated with this chemical compound. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates Olfr578 by interacting with its binding site and initiating signal transduction events in the olfactory sensory neurons. This leads to the perception of fruity odors, as Olfr578 is sensitive to this chemical. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol acts as an activator for Olfr578 by binding to its receptor site, initiating a signaling cascade that triggers olfactory perception. This chemical compound is known for its floral and fruity odor characteristics. | ||||||
1-Octen-3-ol | 3391-86-4 | sc-237604 | 25 g | $49.00 | ||
1-Octen-3-ol serves as an activator for Olfr578 by binding to the receptor site, initiating a signaling cascade within olfactory sensory neurons. This results in the perception of the characteristic mushroom-like odor associated with this chemical. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $46.00 $71.00 $108.00 | ||
Linalool acts as an activator for Olfr578 by binding to its receptor site, initiating signal transduction pathways that lead to the perception of floral and citrusy odors. This chemical compound is known for its aromatic properties. | ||||||
Isovaleric acid | 503-74-2 | sc-250205 | 100 ml | $28.00 | ||
Isovaleric acid activates Olfr578 by binding to its receptor site, triggering signal transduction events within olfactory sensory neurons. This leads to the perception of pungent and cheesy odors associated with this chemical compound. | ||||||
Allyl isothiocyanate | 57-06-7 | sc-252361 sc-252361A sc-252361B | 5 g 100 g 500 g | $43.00 $66.00 $117.00 | 3 | |
Allyl isothiocyanate activates Olfr578 by interacting with its receptor site and initiating a signaling cascade that results in the perception of pungent and spicy odors. This chemical compound specifically activates the olfactory receptor Olfr578. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl salicylate serves as an activator for Olfr578 by binding to its receptor site, initiating signal transduction events within olfactory sensory neurons. This leads to the perception of a characteristic wintergreen odor associated with this compound. | ||||||