Olfr482 Activators
Chemical activators of Olfr482 are proposed based on their potential to interact directly with the olfactory receptor and initiate the G-protein-coupled receptor (GPCR) signaling pathway, a common mechanism in olfactory signal transduction. Compounds such as Butyl acetate, Myrcene, and Citronellal are hypothesized to bind to Olfr482, inducing a change in the receptor's conformation. This binding is thought to trigger the GPCR pathway, leading to an increase in cyclic AMP, a critical second messenger in the olfactory system. The elevation of cyclic AMP levels is vital for converting the chemical signal into a neural signal, which is then transmitted to the brain for olfactory perception.
Other chemicals in this list, like Camphor, Benzyl acetate, and Hexenol, are also considered potential activators of Olfr482 through a similar mechanism. Their unique molecular structures allow for specific interactions with Olfr482, hypothesized to facilitate the receptor's activation. This process underscores the complexity and specialization of olfactory receptors in detecting a diverse array of scents. The interaction of these chemicals with Olfr482 highlights the intricate molecular dynamics involved in olfactory perception and the sophisticated nature of GPCR-mediated signal transduction in the olfactory system.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Butyl acetate | 123-86-4 | sc-214637 sc-214637A | 1 ml 5 ml | $20.00 $79.00 | ||
Butyl acetate, with a fruity aroma, may activate Olfr482 by direct binding, inducing a conformational change in the receptor and initiating the GPCR signaling pathway, potentially resulting in increased cyclic AMP levels crucial for olfactory signal transduction. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal, with a lemon scent, may bind directly to Olfr482, inducing a structural change in the receptor. This activates the GPCR mechanism, leading to increased cyclic AMP and olfactory signal transduction. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $30.00 | 1 | |
Benzyl acetate, commonly associated with jasmine, potentially activates Olfr482 through direct receptor interaction, leading to GPCR pathway activation and an increase in cyclic AMP, facilitating olfactory signal transduction. | ||||||
trans-2-Hexen-1-ol | 928-95-0 | sc-251269 | 25 g | $32.00 | ||
Hexenol, with a green-leaf aroma, might activate Olfr482 by binding to its ligand-binding site. This interaction can trigger the GPCR cascade, increasing cyclic AMP levels, essential for olfactory signaling. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol, with a floral scent, may activate Olfr482 through direct binding to the receptor, triggering the GPCR signaling pathway and resulting in increased cyclic AMP, essential for olfactory signal transduction. | ||||||
α-Ionone | 127-41-3 | sc-239157 | 100 g | $75.00 | ||
α-Ionone, with a violet-like aroma, might activate Olfr482 through direct receptor binding, triggering the GPCR mechanism and increasing cyclic AMP levels, crucial for olfactory signal transduction. | ||||||
(−)-trans-Caryophyllene | 87-44-5 | sc-251281 sc-251281A sc-251281B sc-251281C | 1 ml 5 ml 25 ml 1 L | $81.00 $160.00 $446.00 $2918.00 | 1 | |
β-Caryophyllene, present in cloves and black pepper, potentially activates Olfr482 by direct binding, leading to GPCR pathway activation and a subsequent rise in cyclic AMP, essential for olfactory signaling. | ||||||
α-Humulene | 6753-98-6 | sc-233773 | 1 ml | $204.00 | 1 | |
α-Humulene, a component of hops, may activate Olfr482 through direct interaction with the receptor, initiating the GPCR signaling pathway and resulting in increased cyclic AMP, important for olfactory signal transduction. | ||||||