Date published: 2026-5-20

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α-Humulene (CAS 6753-98-6)

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Alternate Names:
α-Caryophyllene; trans,trans,trans-2,6,6,9-Tetramethyl-1,4,8-cycloundecatriene; alpha-Humulene
Application:
α-Humulene is a useful biochemical for proteomics research
CAS Number:
6753-98-6
Purity:
≥93%
Molecular Weight:
204.35
Molecular Formula:
C15H24
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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α-Humulene, also known as alpha-humulene or α-caryophyllene, is a natural sesquiterpene compound found in various plants, including hops, cannabis, and certain essential oils. It is responsible for the distinctive aroma and flavor of these plants. α-Humulene is known for its potential therapeutic properties, including anti-inflammatory, analgesic, and antibacterial effects. It has been studied for its potential use in traditional medicine and natural remedies. Additionally, α-humulene is a precursor to the production of other terpenes, such as β-caryophyllene, through enzymatic processes.


α-Humulene (CAS 6753-98-6) References

  1. The gas-phase ozonolysis of α-humulene.  |  Beck, M., et al. 2011. Phys Chem Chem Phys. 13: 10970-1001. PMID: 21461420
  2. Analysis of Terpenes in Cannabis sativa L. Using GC/MS: Method Development, Validation, and Application.  |  Ibrahim, EA., et al. 2019. Planta Med. 85: 431-438. PMID: 30646402
  3. Antibacterial and antibiofilm effects of α-humulene against Bacteroides fragilis.  |  Jang, HI., et al. 2020. Can J Microbiol. 66: 389-399. PMID: 32073898
  4. Humulene Inhibits Acute Gastric Mucosal Injury by Enhancing Mucosal Integrity.  |  Yeo, D., et al. 2021. Antioxidants (Basel). 10: PMID: 34064830
  5. Analgesic Potential of Terpenes Derived from Cannabis sativa.  |  Liktor-Busa, E., et al. 2021. Pharmacol Rev. 73: 98-126. PMID: 34663685
  6. Harnessing Yarrowia lipolytica Peroxisomes as a Subcellular Factory for α-Humulene Overproduction.  |  Guo, Q., et al. 2021. J Agric Food Chem. 69: 13831-13837. PMID: 34751575
  7. A review on the traditional uses, phytochemistry, and pharmacological activities of clove basil (Ocimum gratissimum L.).  |  Ugbogu, OC., et al. 2021. Heliyon. 7: e08404. PMID: 34901489
  8. Engineering the oleaginous yeast Candida tropicalis for α-humulene overproduction.  |  Zhang, L., et al. 2022. Biotechnol Biofuels Bioprod. 15: 59. PMID: 35619177
  9. Dual cytoplasmic-peroxisomal engineering for high-yield production of sesquiterpene α-humulene in Yarrowia lipolytica.  |  Guo, Q., et al. 2022. Biotechnol Bioeng. 119: 2819-2830. PMID: 35798689
  10. Effect of alpha-humulene incorporation on the properties of experimental light-cured periodontal dressings.  |  Rossato, TCA., et al. 2022. Braz Oral Res. 36: e091. PMID: 35830138
  11. Anti-inflammatory effects of α-humulene and β-caryophyllene on pterygium fibroblasts.  |  Viveiros, MMH., et al. 2022. Int J Ophthalmol. 15: 1903-1907. PMID: 36536965
  12. Fermentative α-Humulene Production from Homogenized Grass Clippings as a Growth Medium.  |  Langsdorf, A., et al. 2022. Molecules. 27: PMID: 36557817
  13. High-yield α-humulene production in Yarrowia lipolytica from waste cooking oil based on transcriptome analysis and metabolic engineering.  |  Guo, Q., et al. 2022. Microb Cell Fact. 21: 271. PMID: 36566177

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Humulene, 1 ml

sc-233773
1 ml
$204.00