Olfr455 Activators
Or10ac1, a member of the olfactory receptor gene family, stands as a pivotal component in the complex sensory system of olfaction. Its fundamental role involves initiating the neuronal response essential for perceiving specific smells. Or10ac1 achieves this by directly binding to various chemicals, such as Menthol, Isoamyl Acetate, and Cinnamaldehyde, leading to an up-regulation of its activity. These direct activators trigger a cascade of events within the olfactory signaling pathway, enhancing the perception of specific odors associated with each chemical.
Moreover, Or10ac1 can be indirectly activated by compounds like Alkyl Pyrazines and Methyl Salicylate. Alkyl Pyrazines modulate the cAMP signaling pathway, leading to an enhanced expression of Or10ac1 and a heightened response to savory odors. Methyl Salicylate, on the other hand, influences the NF-κB pathway, contributing to increased Or10ac1 expression and an up-regulation of its activity. The intricate interplay between direct and indirect activators showcases the versatility of Or10ac1 in responding to a diverse array of odors. In summary, Or10ac1's activation is a finely orchestrated process involving direct binding to specific chemicals and the modulation of crucial signaling pathways. This ensures the responsiveness of the olfactory system to a wide range of olfactory stimuli, contributing to the intricate and nuanced experience of smell perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $39.00 $68.00 | ||
Menthol, an agonist of TRPM8, directly activates Or10ac1 by stimulating the cold receptor TRPM8. This activation triggers a cascade of intracellular events, ultimately leading to an up-regulation of Or10ac1 expression and an enhanced response to olfactory stimuli associated with menthol. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate directly activates Or10ac1 by binding to its olfactory receptor site. This interaction amplifies the neuronal response to specific fruity odors, leading to an up-regulation of Or10ac1 activity. The direct binding of Isoamyl Acetate to Or10ac1 initiates the olfactory signaling cascade, enhancing the perception of fruity aromas. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamaldehyde, an aldehyde, directly activates Or10ac1 by binding to its olfactory receptor site. This interaction triggers a heightened response to cinnamon odors, resulting in an up-regulation of Or10ac1 activity. The direct binding of Cinnamaldehyde to Or10ac1 initiates the olfactory signaling cascade, enhancing the perception of cinnamon aromas. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone, a ketone, directly activates Or10ac1 by interacting with its olfactory receptor site. This interaction amplifies the neuronal response to specific fruity odors, leading to an up-regulation of Or10ac1 activity. The direct binding of 2-Heptanone to Or10ac1 initiates the olfactory signaling cascade, enhancing the perception of fruity aromas. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal, an aldehyde, directly activates Or10ac1 by binding to its olfactory receptor site. This interaction triggers a heightened response to specific green and grassy odors, resulting in an up-regulation of Or10ac1 activity. The direct binding of Hexanal to Or10ac1 initiates the olfactory signaling cascade, enhancing the perception of green and grassy aromas. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, a phenylpropanoid, directly activates Or10ac1 by binding to its olfactory receptor site. This interaction amplifies the neuronal response to specific spicy odors, leading to an up-regulation of Or10ac1 activity. The direct binding of Eugenol to Or10ac1 initiates the olfactory signaling cascade, enhancing the perception of spicy aromas. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
D-Limonene, a monoterpene, directly activates Or10ac1 by binding to its olfactory receptor site. This interaction amplifies the neuronal response to citrus odors, leading to an up-regulation of Or10ac1 activity. The direct binding of Limonene to Or10ac1 initiates the olfactory signaling cascade, enhancing the perception of citrus aromas. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal, an aldehyde, directly activates Or10ac1 by interacting with its olfactory receptor site. This interaction amplifies the neuronal response to specific citrus odors, leading to an up-regulation of Or10ac1 activity. The direct binding of Octanal to Or10ac1 initiates the olfactory signaling cascade, enhancing the perception of citrus aromas. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin, a phenolic aldehyde, directly activates Or10ac1 by binding to its olfactory receptor site. This interaction triggers a heightened response to vanilla-like odors, resulting in an up-regulation of Or10ac1 activity. The direct binding of Vanillin to Or10ac1 initiates the olfactory signaling cascade, enhancing the perception of vanilla aromas. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl Salicylate, an ester, indirectly activates Or10ac1 by influencing the NF-κB signaling pathway. Its impact on NF-κB enhances Or10ac1 expression, contributing to an up-regulation of its activity. This indirect activation amplifies the neuronal response to specific wintergreen-like odors, associated with Methyl Salicylate, leading to enhanced Or10ac1 activity through NF-κB modulation. | ||||||