Date published: 2026-4-1

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Olfr449 Activators

Chemical activators of Olfr449 play a significant role in the sensory perception of various esters and aromatic compounds. Propyl Acetate and Ethyl Benzoate, for instance, bind to Olfr449, triggering a conformational change that activates the G-protein coupled receptor. This activation leads to a signaling cascade within the olfactory sensory neurons, enhancing the perception of odors characteristic of these compounds. Methyl Salicylate and Isopentyl Acetate function as agonists, inducing structural changes in Olfr449 and initiating downstream events that amplify the olfactory signal.

Furthermore, Ethyl Propionate, Butyl Butyrate, and Ethyl Caproate interact directly with Olfr449, activating the receptor and triggering G-protein coupled signaling mechanisms. This enhances the perception of odors associated with these esters. Hexyl Acetate, Isoamyl Butyrate, Ethyl Lactate, Benzyl Alcohol, and Ethyl Acetate also contribute significantly to this process. They bind to Olfr449 and initiate a signaling cascade that results in an enhanced perception of their related odors. These chemicals, through their specific interactions with Olfr449, effectively activate the olfactory receptor, leading to an enhanced sensory experience of a diverse array of esters and aromatic odors. Their ability to bind and activate Olfr449 plays a crucial role in the functional activation of this olfactory receptor, contributing to the complex and nuanced nature of olfactory perception.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Propyl acetate

109-60-4sc-250792
500 ml
$20.00
(0)

Propyl Acetate activates Olfr449 by binding to its specific receptor site. This binding triggers a conformational change in the receptor, leading to the activation of the associated G-protein. This activation initiates a signaling cascade within olfactory sensory neurons, directly enhancing the perception of odors characteristic of Propyl Acetate.

Methyl Salicylate

119-36-8sc-204802
sc-204802A
250 ml
500 ml
$47.00
$70.00
(1)

Methyl Salicylate functions as an agonist to Olfr449. Its binding induces a structural change in the receptor, enabling G-protein activation. This initiates a series of downstream events that amplify the olfactory signal, enhancing the sensory response to Methyl Salicylate.

Isopentyl acetate

123-92-2sc-250190
sc-250190A
100 ml
500 ml
$107.00
$225.00
(0)

Isopentyl Acetate specifically binds to Olfr449, triggering the activation of the G-protein coupled receptor. This interaction enhances olfactory signal transduction, leading to an increased perception of Isopentyl Acetate-related odors.

Ethyl propionate

105-37-3sc-214997
sc-214997A
25 ml
500 ml
$15.00
$40.00
(0)

Ethyl Propionate activates Olfr449 by binding to the receptor, causing a conformational change that initiates G-protein activation. This leads to a cascade of intracellular events, increasing sensory response to odors similar to Ethyl Propionate.

Butyl butyrate

109-21-7sc-239439
250 ml
$210.00
(0)

Butyl Butyrate directly interacts with Olfr449 as an agonist. This binding triggers the receptor's G-protein coupled signaling mechanism, enhancing the sensory perception of Butyl Butyrate-associated odors.

Ethyl hexanoate

123-66-0sc-235049
5 ml
$51.00
(0)

Ethyl hexanoate activates Olfr449 by binding to its receptor site, initiating the activation of the associated G-protein and leading to a signaling cascade that amplifies olfactory signal transduction for Ethyl Caproate.

Hexyl acetate

142-92-7sc-215149
sc-215149A
25 ml
500 ml
$32.00
$57.00
(0)

Hexyl Acetate, upon binding to Olfr449, activates the G-protein coupled receptor mechanism. This interaction results in enhanced perception of smell, particularly for odors similar to Hexyl Acetate.

Isopentyl butyrate

106-27-4sc-269267
100 g
$67.00
(0)

Isopentyl butyrate engages Olfr449 as an agonist, inducing a change in the receptor's structure and activating the G-protein. This leads to downstream events that amplify the olfactory signal, enhancing sensory response to Isoamyl Butyrate.

Benzyl alcohol

100-51-6sc-326216B
sc-326216
sc-326216A
250 ml
1 L
5 L
$32.00
$104.00
$416.00
(0)

Benzyl Alcohol interacts with Olfr449, activating the receptor and leading to a series of intracellular events that culminate in an increased sensory response to Benzyl Alcohol and similar odorants.

Ethyl Acetate, HPLC

141-78-6sc-360247
sc-360247A
1 L
4 L
$122.00
$326.00
(0)

Ethyl Acetate binds and activates Olfr449, initiating a G-protein coupled receptor signaling cascade. This leads to an increased intracellular calcium level, enhancing the sensory perception of Ethyl Acetate and related odors.