Olfr447 Activators
Chemical activators of Olfr447 play an essential role in the sensory perception of various odors. Ethyl Acetate and Isoamyl Acetate, for example, bind to Olfr447, triggering a conformational change that activates the G-protein coupled receptor. This activation leads to a signaling cascade within the olfactory sensory neurons, enhancing the perception of odors characteristic of these esters. Methyl Salicylate and Benzaldehyde function as agonists, inducing structural changes in Olfr447 and initiating downstream events that amplify the olfactory signal.
Additionally, Ethyl Butyrate and Hexyl Acetate interact directly with Olfr447, activating the receptor and triggering G-protein coupled signaling mechanisms. This enhances the perception of odors associated with these compounds. Citronellol, Geraniol, Linalool, Limonene, Alpha-Pinene, and Beta-Pinene also contribute significantly. They bind to Olfr447 and initiate a signaling cascade that results in an enhanced perception of their related odors. These chemicals, through their specific interactions with Olfr447, effectively activate the olfactory receptor, leading to an enhanced sensory experience of a diverse array of odors, mainly composed of floral and citrus notes. Their ability to bind and activate Olfr447 plays a crucial role in the functional activation of this olfactory receptor, contributing to the complex and nuanced nature of olfactory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $120.00 $320.00 | ||
Ethyl Acetate activates Olfr447 by binding to its specific receptor site. This binding triggers a conformational change in the receptor, leading to the activation of the associated G-protein. This activation initiates a signaling cascade within olfactory sensory neurons, directly enhancing the perception of odors characteristic of Ethyl Acetate. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate, upon binding to Olfr447, activates the G-protein coupled receptor. This leads to an increase in intracellular cyclic AMP, activating protein kinase A and resulting in signal transduction associated with the sensory perception of Isoamyl Acetate-related smells. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl Salicylate functions as an agonist to Olfr447. Its binding induces a structural change in the receptor, enabling G-protein activation. This initiates a series of downstream events that amplify the olfactory signal, enhancing the sensory response to Methyl Salicylate. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl Butyrate activates Olfr447 by binding to the receptor, causing a conformational change that initiates G-protein activation. This leads to a cascade of intracellular events, increasing sensory response to odors similar to Ethyl Butyrate. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl Acetate directly interacts with Olfr447 as an agonist. This binding triggers the receptor's G-protein coupled signaling mechanism, enhancing the sensory perception of Hexyl Acetate-associated odors. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $31.00 $153.00 | ||
(±)-β-Citronellol activates Olfr447 by binding to its receptor site, initiating the activation of the associated G-protein and leading to a signaling cascade that amplifies olfactory signal transduction for Citronellol. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol, upon binding to Olfr447, activates the G-protein coupled receptor mechanism. This interaction results in enhanced perception of smell, particularly for odors similar to Geraniol. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $46.00 $71.00 $108.00 | ||
Linalool engages Olfr447 as an agonist, inducing a change in the receptor's structure and activating the G-protein. This leads to downstream events that amplify the olfactory signal, enhancing sensory response to Linalool. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
D-Limonene binds to Olfr447, causing activation of the G-protein coupled receptor. This interaction initiates a signaling cascade, increasing intracellular calcium levels essential for olfactory signal transduction, thereby enhancing perception of Limonene-related odors. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $51.00 $113.00 | 2 | |
Alpha-Pinene interacts with Olfr447, activating the receptor and leading to a series of intracellular events that culminate in an increased sensory response to Alpha-Pinene and similar odorants. | ||||||