Olfr446 Activators
Chemical activators of Olfr446 play a crucial role in the sensory perception of various aromatic compounds. Benzyl Acetate and Phenethyl Alcohol, for example, bind to Olfr446, triggering a conformational change that activates the G-protein coupled receptor. This activation leads to a signaling cascade within the olfactory sensory neurons, enhancing the perception of odors characteristic of these compounds. Ethyl Salicylate and Isoamyl Acetate function as agonists, inducing structural changes in Olfr446 and initiating downstream events that amplify the olfactory signal.
Additionally, Methyl Anthranilate, Citral, and Linalool interact directly with Olfr446, activating the receptor and triggering G-protein coupled signaling mechanisms. This enhances the perception of odors associated with these chemicals. Geraniol, Limonene, Eugenol, Alpha-Pinene, and Beta-Pinene also contribute significantly to this process. They bind to Olfr446 and initiate a signaling cascade that results in an enhanced perception of their related odors. These chemicals, through their specific interactions with Olfr446, effectively activate the olfactory receptor, leading to an enhanced sensory experience of a diverse array of aromatic odors. Their ability to bind and activate Olfr446 plays a crucial role in the functional activation of this olfactory receptor, contributing to the complex and nuanced nature of olfactory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $29.00 | 1 | |
Benzyl Acetate activates Olfr446 by binding to its specific receptor site. This binding triggers a conformational change in the receptor, leading to the activation of the associated G-protein. This activation initiates a signaling cascade within olfactory sensory neurons, directly enhancing the perception of odors characteristic of Benzyl Acetate. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $68.00 | ||
2-Phenylethanol, upon binding to Olfr446, activates the G-protein coupled receptor. This leads to an increase in intracellular cyclic AMP, activating protein kinase A and resulting in signal transduction associated with the sensory perception of Phenethyl Alcohol-related smells. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate specifically binds to Olfr446, triggering the activation of the G-protein coupled receptor. This interaction enhances olfactory signal transduction, leading to an increased perception of Isoamyl Acetate-related odors. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral directly interacts with Olfr446 as an agonist. This binding triggers the receptor's G-protein coupled signaling mechanism, enhancing the sensory perception of Citral-associated odors. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $46.00 $71.00 $108.00 | ||
Linalool activates Olfr446 by binding to its receptor site, initiating the activation of the associated G-protein and leading to a signaling cascade that amplifies olfactory signal transduction for Linalool. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol, upon binding to Olfr446, activates the G-protein coupled receptor mechanism. This interaction results in enhanced perception of smell, particularly for odors similar to Geraniol. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
D-Limonene engages Olfr446 as an agonist, inducing a change in the receptor's structure and activating the G-protein. This leads to downstream events that amplify the olfactory signal, enhancing sensory response to Limonene. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol binds to Olfr446, causing activation of the G-protein coupled receptor. This interaction initiates a signaling cascade, increasing intracellular calcium levels essential for olfactory signal transduction, thereby enhancing perception of Eugenol-related odors. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $51.00 $113.00 | 2 | |
Alpha-Pinene interacts with Olfr446, activating the receptor and leading to a series of intracellular events that culminate in an increased sensory response to Alpha-Pinene and similar odorants. | ||||||