Chemical activators of Olfr441 significantly contribute to the sensory perception of a range of aldehyde odors. Octanal, Nonanal, Decanal, and Dodecanal, for instance, bind to Olfr441, triggering a conformational change that activates the G-protein coupled receptor. This activation initiates a signaling cascade within the olfactory sensory neurons, enhancing the perception of odors characteristic of these chemicals. Tridecanal, Tetradecanal, Pentadecanal, and Hexadecanal act as agonists, inducing structural changes in Olfr441 and initiating downstream events that amplify the olfactory signal.
Furthermore, Heptadecanal, Octadecanal, Nonadecanal, and Eicosanal directly interact with Olfr441, activating the receptor and triggering G-protein coupled signaling mechanisms. This interaction enhances the perception of odors associated with these chemicals. These aldehydes, through their specific interactions with Olfr441, effectively activate the olfactory receptor, leading to an enhanced sensory experience of a diverse array of odors, mainly in the aldehyde family. Their ability to bind and activate Olfr441 plays a crucial role in the functional activation of this olfactory receptor, contributing to the complex and nuanced nature of olfactory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal activates Olfr441 by binding to its specific receptor site. This binding triggers a conformational change in the receptor, leading to the activation of the associated G-protein. This activation initiates a signaling cascade within olfactory sensory neurons, directly enhancing the perception of odors characteristic of Octanal. | ||||||
Nonanal | 124-19-6 | sc-257926 | 1 g | $67.00 | ||
Nonanal, upon binding to Olfr441, activates the G-protein coupled receptor. This leads to an increase in intracellular cyclic AMP, activating protein kinase A and resulting in signal transduction associated with the sensory perception of Nonanal-related smells. | ||||||
Decanal | 112-31-2 | sc-234518 | 25 g | $43.00 | ||
Decanal functions as an agonist to Olfr441. Its binding induces a structural change in the receptor, enabling G-protein activation. This initiates a series of downstream events that amplify the olfactory signal, enhancing the sensory response to Decanal. | ||||||
Eicosane | 112-95-8 | sc-255135 | 1 g | $20.00 | ||
Eicosane binds and activates Olfr441, initiating a G-protein coupled receptor signaling cascade. This leads to an increased intracellular calcium level, enhancing the sensory perception of Eicosanal and related odors. | ||||||