Olfr402 Activators

Chemical activators of Olfr402 serve a crucial role in initiating the neuronal response associated with the perception of specific odors. These selected chemicals function as direct activators by binding to the olfactory receptor site of Olfr402, thereby inducing a functional activation of the protein. Isoamyl acetate, for instance, engages Olfr402 by forming a specific interaction with its receptor, leading to the initiation of the neuronal response. Similarly, Ethyl vanillin and Allyl isothiocyanate activate Olfr402 by directly binding to the receptor site, enabling the transduction of odorant signals.

In addition to direct activators, other chemicals like Geraniol, Methyl salicylate, Eugenol, Benzaldehyde, Citronellol, Linalool, Hexanal, Limonene, and Methyl cinnamate also play a pivotal role in Olfr402 activation. These chemicals, when inhaled or detected, engage the olfactory receptors and trigger the specific neuronal response responsible for odor perception. Each chemical listed in the table serves as a unique activator for Olfr402, binding to its receptor site and initiating the sensory process associated with the recognition and interpretation of distinct smells. The direct activation of Olfr402 by these chemicals is a fundamental step in the intricate mechanism of olfaction, allowing for the perception of a wide range of odorant molecules.