Olfr374 Activators
Chemical activators of Or1ab2, a G-protein-coupled olfactory receptor, exhibit a range of mechanisms that specifically interact with and activate this receptor. Compounds like Methyl anthranilate, Ethyl hexanoate, and Ethyl butyrate bind to the GPCR structure of Or1ab2. This binding triggers conformational changes in the receptor, which are essential for its activation and effective transduction of olfactory signals via G protein-coupled pathways. The specificity of these interactions is crucial for enhancing Or1ab2's ability to recognize and respond to different odorants.
Furthermore, chemicals such as Ethyl 2-methylbutyrate, Hexyl acetate, Octanal, and Phenethyl alcohol demonstrate similar activation mechanisms. They interact with various domains of Or1ab2, causing structural modifications that lead to the receptor's functional activation. This activation is pivotal for the initiation of G protein-coupled odorant signal transduction processes. Additionally, activators like Geranyl acetone, 2-Nonanone, Decanal, Anisole, and Benzaldehyde engage with the receptor's structure, resulting in conformational changes that potentiate Or1ab2's olfactory signal transduction capabilities. Each of these chemicals contributes to the functional activation of Or1ab2 by influencing its structural and conformational dynamics, which are critical for effective olfactory signal transduction and perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $51.00 | ||
Ethyl hexanoate interacts with Or1ab2, facilitating its activation through binding to the olfactory receptor domain, enhancing odorant signal recognition and transduction. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates Or1ab2 by engaging its ligand-binding site, causing a structural alteration that leads to the initiation of G protein-coupled olfactory signaling pathways. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate activates Or1ab2 by interacting with its extracellular domain, leading to a conformational change and the activation of G protein-coupled intracellular signaling related to olfaction. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal engages Or1ab2, activating it by altering its conformation and thereby enhancing the receptor's ability to initiate olfactory signal transduction processes. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol activates Or1ab2 by binding to its GPCR domain, causing a structural shift that enables the initiation of G protein-coupled odorant signal transduction. | ||||||
Geranylacetone | 3796-70-1 | sc-250051 sc-250051A sc-250051B sc-250051C | 25 g 100 g 500 g 1 kg | $116.00 $206.00 $775.00 $1244.00 | ||
Geranylacetone interacts with Or1ab2, causing a conformational alteration that leads to the activation of G protein-coupled signaling mechanisms specific to olfactory perception. | ||||||
2-Nonanone | 821-55-6 | sc-238184 sc-238184A | 5 g 100 g | $47.00 $84.00 | ||
2-Nonanone binds to Or1ab2's ligand-binding region, inducing a conformational change that facilitates G protein-coupled odorant signal transduction. | ||||||
Decanal | 112-31-2 | sc-234518 | 25 g | $43.00 | ||
Decanal activates Or1ab2 by engaging with its extracellular domain, leading to a structural alteration that triggers G protein-mediated olfactory signal transduction. | ||||||
Anisole | 100-66-3 | sc-233877 sc-233877A | 500 ml 2.5 L | $65.00 $204.00 | ||
Anisole interacts directly with Or1ab2, causing a conformational shift that activates the receptor and enhances its ability to transduce olfactory signals through G protein-mediated pathways. | ||||||