Olfr361 Activators
Chemical activators of Olfr361 can directly engage this olfactory receptor through a variety of aromatic compounds that are capable of binding to its ligand-binding domain. Anethole, eugenol, and isoeugenol are examples of such chemicals, each with a distinct structural affinity for Olfr361. These compounds can initiate a conformational change in Olfr361, leading to the activation of intracellular signal transduction pathways specifically connected to olfactory sensing. The direct interaction between these chemicals and Olfr361 is essential for the functional activation of the receptor, which is a critical initial step in the olfactory signaling cascade.
Other activators, such as isoamyl acetate, limonene, and methyl salicylate, operate on the same principle of direct binding and activation. Isoamyl acetate's banana-like odor and limonene's citrus scent engage Olfr361 by fitting into its ligand-binding site, thereby initiating activation. Methyl salicylate, with its wintergreen scent, and benzaldehyde, known for its almond-like aroma, also activate Olfr361 by direct interaction, which is crucial for the subsequent activation of the olfactory signaling pathway. Heptanal, octanal, 2-phenylethanol, alpha-pinene, and beta-caryophyllene, each with their own unique scents ranging from fruity and green to pine-like and woody, also participate in the activation of Olfr361 by docking at the receptor's ligand-binding site, which triggers the protein's activation and promotes signal transduction associated with olfaction.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $565.00 $310.00 | ||
Anethole is known to activate olfactory receptors and, by extension, may directly activate Olfr361 by binding to its specific site on the receptor, causing a conformational change that initiates signal transduction. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol activates olfactory receptors due to its fragrant nature. It interacts directly with Olfr361, presumably at its ligand-binding domain, to initiate olfactory signal transduction. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isoamyl acetate, with its banana-like odor, is a known activator of olfactory receptors and may engage Olfr361 by binding to the receptor's ligand-binding site, triggering activation and signal transduction. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
Limonene, a citrus-scented molecule, can activate Olfr361 by directly interacting with the receptor’s ligand-binding domain, inducing an active conformation and facilitating signal transduction. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl salicylate, with its wintergreen scent, can activate Olfr361 by binding to the receptor, promoting a conformational change that leads to the activation of downstream signaling cascades. | ||||||
Heptaldehyde | 111-71-7 | sc-250089 sc-250089A | 2 ml 100 ml | $29.00 $58.00 | ||
Heptanal, which has a fruity, green odor, can activate Olfr361 through direct binding to the receptor's ligand-binding site, initiating signal transduction pathways. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $25.00 $33.00 | ||
Octanal offers a citrus-like odor and can activate Olfr361 by directly binding to the receptor, which in turn activates the olfactory signaling cascade. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $68.00 | ||
2-Phenylethanol, with a floral scent, can activate Olfr361 by binding to the receptor's ligand-binding domain, prompting activation and signal transduction. | ||||||
Isoeugenol | 97-54-1 | sc-250186 sc-250186A | 5 g 100 g | $62.00 $52.00 | ||
Isoeugenol is known for activating olfactory receptors through its clove-like scent and can activate Olfr361 by direct interaction at the ligand-binding site, leading to activation of the receptor. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $51.00 $113.00 | 2 | |
Alpha-Pinene, with its pine-like aroma, can activate Olfr361 by direct ligand-receptor interaction, thereby activating the signaling pathway associated with this olfactory receptor. | ||||||