Olfr33 Activators
Chemical activators of Olfr330 exhibit their modulatory effects through various mechanisms, primarily involving the activation of transient receptor potential (TRP) channels and modulation of intracellular ion concentrations. Bisphenol A engages with estrogen receptors that can interact with Olfr330, leading to its activation via estrogen receptor-mediated signaling. Similarly, Icilin acts upon TRPM8 channels, resulting in ion flow changes that ultimately affect Olfr330 activity. Zinc Pyrithione, by increasing intracellular zinc levels, influences signaling pathways that converge on Olfr330. Eugenol's activation of TRPV1 channels alters local ion concentrations, which in turn can modulate Olfr330. Methyl Salicylate operates through TRPA1 channels, affecting intracellular calcium levels that are critical for the activation of Olfr330.
Continuing with the theme of TRP channel activation, Capsaicin, known for its effect on TRPV1 channels, causes an influx of calcium ions that can activate Olfr330. Menthol's action on TRPM8 channels also induces changes in cellular ion homeostasis that can activate Olfr330. Thymol and Geraniol have similar effects; Thymol activates TRPM8 and TRPV3 channels, while Geraniol acts on TRPV2 channels, both resulting in intracellular ion level alterations that can influence Olfr330 activity. Citral, which activates TRPM8 channels, and Cinnamaldehyde, which acts on TRPA1 channels, both lead to changes in ion currents and calcium levels, respectively, affecting Olfr330 signaling pathways. Lastly, Alpha-Terpineol's activation of TRPM8 channels also modulates signaling pathways, impacting Olfr330's activity through its effect on ion currents within cells.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Bisphenol A can bind to and activate estrogen receptors which are linked with olfactory receptors like Olfr330, leading to the activation of Olfr330 through estrogen receptor-mediated signaling pathways. | ||||||
Icilin | 36945-98-9 | sc-201557 sc-201557A | 10 mg 50 mg | $91.00 $257.00 | 9 | |
Icilin activates transient receptor potential (TRP) channels, specifically TRPM8, which can lead to changes in ion flow. This modulation of ion channels can result in the activation of Olfr330 as it alters olfactory signal transduction. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc Pyrithione can increase intracellular zinc concentrations, which can act as a signaling molecule. Elevated zinc levels can activate pathways that lead to the activation of Olfr330, as zinc can influence olfactory receptor signaling. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol is known to activate TRP channels, such as TRPV1, which can influence the activity of adjacent olfactory receptors including Olfr330, leading to its activation through local changes in ion concentrations. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl Salicylate can activate TRPA1 channels, influencing the intracellular calcium levels. This can activate Olfr330 by modulating the calcium-dependent signaling pathways associated with olfactory transduction. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin is a known activator of TRPV1 channels, which can cause an influx of calcium ions. This activation can extend to Olfr330, as the alteration in calcium levels can affect the signaling pathways Olfr330 is involved in. | ||||||
(−)-Menthol | 2216-51-5 | sc-202705 sc-202705A | 1 g 50 g | $20.00 $41.00 | 2 | |
Menthol can activate TRPM8 channels, causing changes in cellular ion homeostasis. These changes can lead to the activation of Olfr330 by affecting the ion-dependent signaling mechanisms of olfactory receptors. | ||||||
Thymol | 89-83-8 | sc-215984 sc-215984A | 100 g 500 g | $97.00 $193.00 | 3 | |
Thymol has been shown to activate TRPM8 and TRPV3 channels, which may result in the alteration of intracellular ion levels, leading to the activation of Olfr330 through the affected signaling pathways. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol can activate TRPV2 channels, which could lead to the activation of Olfr330 by altering intracellular calcium levels that are crucial for olfactory receptor activity. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral has been observed to activate TRPM8 channels, influencing intracellular ion currents. This interaction can activate Olfr330 as it may impact the ion-mediated signaling pathways that olfactory receptors participate in. | ||||||