Olfr314 Inhibitors
Inhibitors targeting a specific olfactory receptor are key agents in adjusting the receptor's ability to sense and respond to odors. These molecules work by competitively occupying the scent detection sites on the receptor, effectively blocking the natural activation by its intended ligands. Certain aromatic compounds are especially effective, taking up these critical sites and thereby diminishing the receptor's capacity to register other odorant molecules. Other blockers latch onto these ligand-binding regions, preventing the normal activation by their natural counterparts. Some scent-related molecules also engage in this competitive interaction at the active sites, leading to reduced functionality of the receptor. Additionally, certain inhibitors don't just block scent molecules but also alter the sensitivity of the receptor by affecting its temperature-sensitive aspects.
Furthermore, a subset of inhibitors reduces the receptor's activity by making the sensory neurons less responsive to odors, thus decreasing the overall activity of the receptor. Molecules with citrus or terpenoid characteristics take part in this competitive inhibition as well, diminishing the receptor's responsiveness to these particular types of odors. Some compounds, due to their high affinity for the receptor, serve as strong inhibitors. They prevent the usual odorant molecule binding and detection that the receptor is designed for.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
This aromatic alcohol specifically targets olfactory receptors like Olfr314 by binding to the receptor site, thus inhibiting the receptor's ability to detect other odorant molecules. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Acts on olfactory receptors by binding competitively to the same sites as natural odorants, which results in decreased sensitivity and activity of receptors including Olfr314. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
This ester is known to interact with olfactory receptors and can inhibit the function of Olfr314 by providing competitive binding to the receptor's active site. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $39.00 $68.00 | ||
As a cooling agent, menthol can modulate the sensitivity of temperature-sensitive olfactory receptors, leading to a functional inhibition of receptors including Olfr314. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
By binding to the olfactory receptor sites, this aldehyde can decrease the sensitivity and activation of olfactory receptors like Olfr314. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
This citrus-scented compound binds to olfactory receptors, competitively inhibiting the activation of receptors such as Olfr314 by natural citrus odorants. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Known to influence sensory neurons, capsaicin can indirectly inhibit olfactory receptors like Olfr314 by desensitizing the sensory neurons responsible for odor detection. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
This compound can bind to the same sites as other terpenoid odorants on olfactory receptors, thereby reducing the functional activity of Olfr314. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Interacts with olfactory receptors by competitively inhibiting the natural ligand-binding, thus decreasing the functional activation of receptors such as Olfr314. | ||||||