Date published: 2025-12-22

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Olfr1098 Inhibitors

The chemical class of "Olfr1098 Inhibitors," in this context, refers to compounds that can indirectly affect the function of Olfr1098 by modulating signaling pathways or cellular processes relevant to G-protein coupled receptors (GPCRs). These inhibitors do not bind directly to Olfr1098 but can influence its activity through various mechanisms. GPCRs, including olfactory receptors like Olfr1098, function through the interaction with G-proteins, which in turn activate or inhibit various downstream effectors, primarily involving the production or modulation of secondary messengers like cAMP. Compounds like Forskolin, which enhances cAMP production by activating adenylate cyclase, and Propranolol, a beta-adrenergic antagonist that influences cAMP pathways, exemplify how altering these messengers can indirectly affect GPCR function.

Another approach to modulate GPCR activity is by influencing the membrane environment or intracellular trafficking. Cholesterol is crucial for membrane fluidity, which is essential for the proper functioning of membrane proteins, including GPCRs. Brefeldin A disrupts the Golgi apparatus, potentially affecting the trafficking and expression of GPCRs on the cell surface. Ion channels and enzymatic pathways also play a role in GPCR signaling. Amiloride affects ion channels, which can modify the cellular response to GPCR activation. Genistein, as a tyrosine kinase inhibitor, might influence the phosphorylation status of proteins involved in GPCR signaling pathways. The indirect inhibitors listed target various aspects of cell signaling and membrane dynamics, providing a broad approach to modulating Olfr1098 function. This approach is significant given the current lack of direct inhibitors for many olfactory receptors, allowing for potential modulation of their activity through broader cellular mechanisms.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Suramin sodium

129-46-4sc-507209
sc-507209F
sc-507209A
sc-507209B
sc-507209C
sc-507209D
sc-507209E
50 mg
100 mg
250 mg
1 g
10 g
25 g
50 g
$149.00
$210.00
$714.00
$2550.00
$10750.00
$21410.00
$40290.00
5
(1)

Suramin is known to interfere with G-protein coupled receptor signaling, which might indirectly affect Olfr1098's function.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$30.00
$52.00
$122.00
$367.00
25
(3)

This compound disrupts Golgi apparatus function, potentially influencing the trafficking of GPCRs like Olfr1098.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein is a tyrosine kinase inhibitor that could indirectly modify GPCR signaling pathways.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin activates adenylate cyclase, potentially altering cAMP levels and indirectly influencing GPCR activity.

Propranolol

525-66-6sc-507425
100 mg
$180.00
(0)

As a beta-adrenergic antagonist, propranolol might affect cAMP pathways linked with GPCR signaling.

Cholesterol

57-88-5sc-202539C
sc-202539E
sc-202539A
sc-202539B
sc-202539D
sc-202539
5 g
5 kg
100 g
250 g
1 kg
25 g
$26.00
$2754.00
$126.00
$206.00
$572.00
$86.00
11
(1)

Cholesterol is crucial for maintaining membrane fluidity, which is vital for the function of membrane proteins like GPCRs.

Clozapine

5786-21-0sc-200402
sc-200402A
50 mg
500 mg
$68.00
$357.00
11
(1)

An antipsychotic known to interact with various GPCRs, possibly influencing Olfr1098 signaling.

Amiloride

2609-46-3sc-337527
1 g
$290.00
7
(1)

Amiloride, primarily a diuretic, can interfere with ion channels, potentially affecting GPCR signaling pathways.

Lidocaine

137-58-6sc-204056
sc-204056A
50 mg
1 g
$50.00
$128.00
(0)

This local anesthetic might alter membrane properties, indirectly impacting GPCR activity.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$32.00
$66.00
$95.00
$188.00
$760.00
13
(1)

Caffeine, a known adenosine receptor antagonist, might affect cAMP pathways associated with GPCR signaling.