Olfr1049 Activators
Olfr1049, an olfactory receptor, plays a pivotal role in the detection and transduction of odorant signals, and its functional activity is modulated by various chemical compounds. Isoamyl acetate, Benzaldehyde, and 2-Heptanone, with their distinct scents, serve as direct activators of Olfr1049. When these molecules bind to Olfr1049, they induce a conformational change in the receptor, initiating G-protein-coupled signal transduction pathways. This interaction is crucial for the perception of their respective odors. Similarly, Ethyl butyrate and Citral, both known for their fruity and citrus odors, enhance the activity of Olfr1049 through direct binding. The binding of these molecules to Olfr1049 triggers a cascade of intracellular events leading to the activation of specific neural pathways responsible for olfactory perception. Eugenol and Methyl salicylate, each with unique aromatic properties, also interact with Olfr1049. Their binding to the receptor facilitates the transduction of olfactory signals, essential for the perception of clove and wintergreen odors, respectively.
Continuing with other activators, Limonene, Vanillin, and Ethyl vanillin interact with Olfr1049 by binding to its ligand-binding site, playing a significant role in the perception of citrus, vanilla, and sweet odors. This interaction leads to the activation of downstream olfactory signaling mechanisms, integral to the process of odor detection and discrimination. Alpha-Pinene and Acetophenone further extend the spectrum of Olfr1049 activation. Alpha-Pinene, with its pine-like aroma, and Acetophenone, known for its sweet and floral scent, bind to Olfr1049, triggering a series of intracellular signaling events. These interactions are critical for the transduction of specific olfactory signals, facilitating the perception of a diverse range of odors. Collectively, these compounds, through their targeted effects on Olfr1049, enhance the receptor's ability to detect and transduce a wide array of olfactory signals, illustrating the complexity and specificity of olfactory perception mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
As an odorant molecule, Isoamyl acetate likely interacts with Olfr1049, a specific olfactory receptor, by binding to its ligand-binding site. This interaction activates the receptor, triggering a G-protein-coupled signal transduction pathway leading to the perception of smell. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone interacts with olfactory receptors like Olfr1049 by binding to their active sites. This binding triggers a cascade of intracellular events, resulting in the transduction of olfactory signals. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, a fruity-smelling ester, can activate Olfr1049 by direct binding. This interaction promotes changes in the receptor structure, leading to the activation of downstream olfactory signal transduction mechanisms. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, known for its citrus odor, can bind to and activate Olfr1049. This binding induces a series of intracellular responses integral to the olfactory signaling pathway, resulting in the perception of citrus smells. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, a component of clove oil, can interact with Olfr1049, potentially activating it. This interaction is likely to facilitate the transduction of olfactory signals through G-protein-mediated pathways. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate can activate Olfr1049 by binding to it, triggering olfactory signal transduction pathways. This interaction is crucial for the perception of its wintergreen odor. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene, a citrus scent compound, is likely to activate Olfr1049 by binding to its active site. This interaction initiates a series of events that culminate in the transduction of olfactory signals. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin can enhance the activity of Olfr1049 by binding to it, which is essential for the perception of its vanilla-like odor through olfactory signal transduction pathways. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
3-Ethoxy-4-hydroxybenzaldehyde, similar to vanillin, activates Olfr1049 through direct interaction, playing a key role in the olfactory perception of its sweet, vanilla-like smell. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
Alpha-Pinene, a component of pine scent, likely activates Olfr1049 by binding, triggering a cascade of intracellular signaling involved in the perception of pine-like odors. | ||||||