Olfr1030 Activators
Olfr1030 activators encompass a diverse range of chemical compounds, each contributing uniquely to the enhancement of Olfr1030's functional activity through specific G protein-coupled receptor (GPCR) pathways. Isoamyl acetate, with its banana-like aroma, is a prime example; upon binding to Olfr1030, it triggers a cascade that elevates intracellular cAMP levels, thereby amplifying the receptor's signaling. Similarly, benzaldehyde and ethyl butyrate, known for their almond and fruity scents, respectively, act as agonists, initiating conformational changes in Olfr1030. This activation results in an enhanced GPCR-mediated signal transduction, specific to this olfactory receptor. Other compounds, such as citral and geraniol, further illustrate this mechanism. Citral, found in lemon oil, and geraniol, with its rose-like scent, bind to Olfr1030's ligand-binding domain, leading to increased cAMP and amplified signaling. Methyl salicylate and linalool, recognized for their wintergreen and floral odors, also bind selectively to Olfr1030, initiating similar GPCR pathways that culminate in heightened receptor activity.
The intricate interplay of these activators with Olfr1030 is further exemplified by compounds like ethyl vanillin, limonene, and cinnamaldehyde. Ethyl vanillin's interaction with Olfr1030, through its vanilla-like aroma, induces GPCR-mediated pathways that enhance the receptor's signaling. Limonene, a citrus peel oil component, and cinnamaldehyde, with its cinnamon scent, act as agonists to Olfr1030, triggering GPCR cascades that result in increased cAMP levels and heightened receptor activity. Heptanal and α-pinene extend this pattern; heptanal, possessing a fruity and slightly oily odor, and α-pinene, a constituent of pine resin, bind to Olfr1030, initiating GPCR signaling that amplifies the receptor's functionality. Collectively, these Olfr1030 activators demonstrate a sophisticated mechanism of action, wherein each compound, through its unique aroma and molecular interaction, selectively enhances the signaling pathways and functional activity of Olfr1030, illustrating the intricate relationship between chemical structure and olfactory receptor activation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
This ester, known for its banana-like odor, is a ligand for Olfr1030. Binding of isoamyl acetate to Olfr1030 triggers a G protein-coupled receptor cascade, leading to an increase in intracellular cAMP, which directly enhances Olfr1030 signaling. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
This compound, known for its fruity odor, selectively binds to Olfr1030. This interaction stimulates a G protein-coupled response, leading to increased intracellular cAMP levels, thereby potentiating Olfr1030-mediated signaling. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, a component of lemon oil, activates Olfr1030 by binding to its ligand-binding domain. This initiates a GPCR pathway, resulting in elevated cAMP and enhanced signal transduction specific to Olfr1030. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
A naturally occurring alcohol with a rose-like scent, geraniol acts as a specific agonist for Olfr1030. Its binding triggers a GPCR-mediated cascade, leading to enhanced signaling through increased intracellular cAMP levels. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Known for its wintergreen scent, methyl salicylate binds and activates Olfr1030. This interaction triggers a G protein-coupled signaling pathway, resulting in the enhancement of Olfr1030-specific signal transduction mechanisms. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $46.00 $71.00 $108.00 | ||
A terpene alcohol with a floral scent, linalool selectively binds to Olfr1030, activating it. This binding initiates GPCR-mediated signaling, leading to an increase in cAMP and enhanced Olfr1030 activity. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
3-Ethoxy-4-hydroxybenzaldehyde, a derivative of vanillin with a vanilla-like aroma, activates Olfr1030 by binding to its active site. This interaction induces GPCR-mediated pathways, resulting in enhanced signaling through Olfr1030. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
A major component of citrus peel oils, limonene acts as an agonist for Olfr1030. Its binding initiates a G protein-coupled receptor cascade, enhancing the signaling efficacy of Olfr1030. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Known for its cinnamon scent, cinnamaldehyde binds to Olfr1030, triggering GPCR-mediated signal transduction. This enhances the functional activity of Olfr1030 through increased intracellular cAMP levels. | ||||||
Heptaldehyde | 111-71-7 | sc-250089 sc-250089A | 2 ml 100 ml | $29.00 $58.00 | ||
Heptanal, with a fruity and slightly oily odor, acts as a ligand for Olfr1030. Its interaction with Olfr1030 initiates G protein-coupled receptor signaling, leading to enhanced activity of this olfactory receptor. | ||||||