Date published: 2026-6-7

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OATP Inhibitors

Santa Cruz Biotechnology now offers a broad range of OATP Inhibitors for use in various applications. OATP (Organic Anion Transporting Polypeptide) inhibitors are pivotal in the study of membrane transport mechanisms, specifically focusing on the modulation of anion transport across cellular membranes. These inhibitors are instrumental in dissecting the molecular intricacies of OATP function, facilitating a deeper understanding of substrate specificity, transport kinetics, and regulatory mechanisms within various biological systems. Researchers employ OATP inhibitors to investigate the transport dynamics of endogenous compounds, such as bile acids, hormones, and bilirubin, as well as exogenous substrates including environmental toxins and dietary constituents. The inhibition of OATP transporters provides critical insights into the cellular uptake and distribution of these compounds, which is essential for explaining their physiological roles and potential toxicological impacts. Furthermore, OATP inhibitors serve as valuable tools in the characterization of transporter interactions and the development of novel analytical techniques for the identification and quantification of transporter substrates. By leveraging these inhibitors, scientists can advance the field of transporter biology, contributing to a more comprehensive understanding of cellular transport processes and their implications in various research contexts. View detailed information on our available OATP Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Naringin

10236-47-2sc-203443
sc-203443A
25 g
50 g
$45.00
$101.00
7
(1)

Naringin exhibits notable interactions with the OATP transporters, characterized by its ability to modulate substrate uptake through competitive inhibition. Its flavonoid structure enhances binding affinity, influencing the transport kinetics of various organic compounds. The compound's unique stereochemistry and hydrophilic properties facilitate its solubility in biological systems, providing insights into the dynamics of nutrient absorption and the regulation of metabolic pathways.

(±)-Sulfinpyrazone

57-96-5sc-202822
sc-202822A
1 g
5 g
$42.00
$94.00
2
(1)

(±)-Sulfinpyrazone is a unique compound that interacts with OATP transporters, exhibiting a distinct mechanism of action through non-competitive inhibition. Its sulfonamide group enhances its affinity for specific substrates, altering their transport dynamics. The compound's stereochemical configuration contributes to its selective binding, influencing the kinetics of organic anion transport. Additionally, its physicochemical properties, such as moderate lipophilicity, play a crucial role in modulating cellular uptake processes.