Date published: 2025-9-15

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Nucleic Acids, Nucleotides and Nucleosides

Santa Cruz Biotechnology now offers a broad range of nucleic acids, nucleotides, and nucleosides for use in various applications. Nucleic acids, including DNA and RNA, are the fundamental molecules of life, encoding the genetic information necessary for the development, functioning, and reproduction of all living organisms. Nucleotides, the building blocks of nucleic acids, and nucleosides, which consist of a nitrogenous base attached to a sugar molecule, play critical roles in numerous biological processes. In scientific research, these compounds are essential for studying genetic expression, regulation, and mutation. They are utilized in techniques such as PCR, sequencing, and gene editing, enabling researchers to explore the complexities of genomes and develop innovative biotechnological applications. Nucleic acids are also pivotal in the study of transcription, translation, and replication, providing insights into cellular mechanisms and the flow of genetic information. In the field of molecular biology, nucleotides and nucleosides are used to investigate enzyme activities, signal transduction pathways, and metabolic processes. Environmental scientists study nucleic acids to monitor biodiversity, track microbial communities, and assess environmental changes. Additionally, in materials science, nucleic acids are harnessed for the development of biosensors, nanomaterials, and bioinformatics tools. The broad applicability and vital roles of nucleic acids, nucleotides, and nucleosides in advancing scientific knowledge and technology make them indispensable tools in research across multiple disciplines. View detailed information on our available nucleic acids, nucleotides, and nucleosides by clicking on the product name.

Items 111 to 120 of 157 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

4-Thiothymidine

7236-57-9sc-284446
sc-284446A
10 mg
25 mg
$66.00
$178.00
(0)

4-Thiothymidine is a modified nucleoside that features a sulfur atom in its structure, which enhances its reactivity and interaction with nucleic acids. This substitution can influence hydrogen bonding patterns, potentially altering base pairing and stability of nucleic acid duplexes. The presence of the thiol group may also facilitate unique redox reactions, impacting the kinetics of nucleic acid synthesis and degradation. Additionally, its distinct electronic properties can affect the absorption spectra, providing insights into molecular interactions in biochemical systems.

5′-N-Ethylcarboxamidoadenosine

35920-39-9sc-291071
sc-291071A
sc-291071B
10 mg
15 mg
50 mg
$82.00
$158.00
$226.00
(1)

5'-N-Ethylcarboxamidoadenosine is a modified nucleoside that exhibits unique interactions with nucleic acids due to its ethylcarboxamide group. This modification can enhance solubility and alter the conformational dynamics of nucleic acid structures, influencing their stability and reactivity. The compound may also participate in specific hydrogen bonding patterns, affecting the kinetics of enzymatic reactions and the overall thermodynamics of nucleic acid hybridization processes.

2′,3′,5′-Tri-O-acetylinosine

3181-38-2sc-220834
1 g
$90.00
(0)

2',3',5'-Tri-O-acetylinosine is a modified nucleoside characterized by its acetyl groups, which enhance its lipophilicity and stability against nucleolytic degradation. This compound can engage in unique stacking interactions with nucleic acids, potentially influencing their structural conformations. The presence of acetyl groups may also modulate the kinetics of phosphorylation reactions, impacting the overall dynamics of nucleotide incorporation during nucleic acid synthesis.

2-Chloro-2′-deoxyadenosine

4291-63-8sc-202399
10 mg
$144.00
1
(0)

2-Chloro-2′-deoxyadenosine is a halogenated nucleoside that exhibits unique interactions with nucleic acids due to its chlorine substituent. This modification can alter hydrogen bonding patterns, potentially affecting base pairing and stability of nucleic acid structures. Its presence may influence the kinetics of enzymatic reactions, such as those involving polymerases, by modifying the binding affinity and catalytic efficiency during nucleotide incorporation. Additionally, the compound's structural features can impact its solubility and reactivity in biochemical pathways.

Ethyl 2-thiouracil-5-carboxylate

38026-46-9sc-280691
5 g
$45.00
(0)

Ethyl 2-thiouracil-5-carboxylate is a versatile compound that interacts with nucleic acids through its thiol and carboxyl functional groups. These groups can form hydrogen bonds and participate in nucleophilic attacks, influencing the stability and reactivity of nucleotides. The compound's unique structure allows it to modulate enzymatic activity, potentially altering reaction rates in nucleic acid metabolism. Its distinct electronic properties may also affect molecular recognition processes, enhancing specificity in biochemical pathways.

6-Benzylaminopurine 9-(α-D-glucoside)

4294-17-1sc-221084
10 mg
$280.00
(0)

6-Benzylaminopurine 9-(β-D-glucoside) is a modified purine nucleoside that showcases distinctive interactions with nucleic acids through its benzylamine moiety. This structural modification can enhance stacking interactions and alter the conformational dynamics of nucleic acid structures. Its glucoside linkage may influence solubility and cellular uptake, while also affecting the kinetics of enzymatic processes, such as phosphorylation and glycosylation, thereby modulating nucleic acid metabolism.

Adenosine 5′-Monophosphate, Disodium Salt

4578-31-8sc-202444
sc-202444A
sc-202444B
sc-202444C
5 g
25 g
100 g
1 kg
$59.00
$158.00
$260.00
$908.00
(1)

Adenosine 5′-Monophosphate, Disodium Salt is a key nucleotide that plays a pivotal role in cellular energy transfer and signaling. Its disodium form enhances solubility, facilitating rapid diffusion across membranes. The molecule participates in crucial biochemical pathways, including ATP synthesis and cyclic AMP formation, influencing various enzymatic reactions. Its ability to form hydrogen bonds and ionic interactions with proteins and nucleic acids underscores its importance in cellular regulation and metabolic processes.

5′-Deoxyadenosine

4754-39-6sc-221057
sc-221057A
25 mg
100 mg
$260.00
$765.00
(0)

5'-Deoxyadenosine is a unique nucleoside that serves as a precursor in the synthesis of various nucleotides. It exhibits distinct molecular interactions, particularly through its ability to form stable hydrogen bonds with complementary bases in nucleic acids. This property enhances its role in DNA synthesis and repair mechanisms. Additionally, its structural features allow for specific enzyme recognition, influencing reaction kinetics in metabolic pathways. Its hydrophobic regions contribute to its interactions within cellular membranes, impacting nucleic acid stability and function.

3′-O-Methylguanosine

10300-27-3sc-283951
sc-283951A
10 mg
25 mg
$113.00
$300.00
(0)

3'-O-Methylguanosine is a modified nucleoside that plays a crucial role in RNA metabolism. Its unique 3'-O-methylation alters hydrogen bonding patterns, influencing RNA structure and stability. This modification can affect the binding affinity of RNA-binding proteins, thereby modulating gene expression and splicing processes. Additionally, its presence in RNA can impact the kinetics of transcription and translation, contributing to the regulation of various cellular pathways.

5′-Amino-5′-deoxyadenosine hydrochloride

14365-44-7sc-284702
sc-284702A
1 mg
5 mg
$204.00
$816.00
(0)

5'-Amino-5'-deoxyadenosine hydrochloride is a nucleoside analog characterized by its amino group at the 5' position, which enhances its hydrogen bonding capabilities. This modification can influence the stability and conformation of nucleic acid structures, potentially affecting enzyme interactions and substrate recognition. Its unique properties may alter the kinetics of nucleic acid synthesis and degradation, thereby impacting various biochemical pathways and cellular processes.