Date published: 2026-5-16

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NP220 Inhibitors

NP220 inhibitors are a class of chemical compounds that specifically target the NP220 protein, also known as ZMYND11. This protein plays a crucial role in chromatin remodeling and transcriptional regulation, particularly in the context of gene silencing. NP220 is involved in the recruitment of chromatin-modifying enzymes and transcriptional repressors to specific genomic loci, thereby regulating gene expression patterns. By inhibiting the activity of NP220, these inhibitors have the potential to alter gene expression profiles in cells, leading to downstream effects on cellular function and phenotype.

The development of NP220 inhibitors represents a promising area of research in the field of chemical biology and epigenetics. Understanding the molecular mechanisms of NP220 function and inhibition could provide valuable insights into gene regulation and chromatin dynamics. Additionally, NP220 inhibitors have the potential to be used as tools in the study of epigenetic mechanisms and gene expression control.

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Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

A-769662

844499-71-4sc-203790
sc-203790A
sc-203790B
sc-203790C
sc-203790D
10 mg
50 mg
100 mg
500 mg
1 g
$184.00
$741.00
$1076.00
$3417.00
$5304.00
23
(2)

As an AMPK activator, A-769662 affects energy regulation pathways. If NP220's function or stability is influenced by energy states or AMPK signaling, its activity could be indirectly modulated.

EX 527

49843-98-3sc-203044
5 mg
$87.00
32
(1)

EX-527 is an inhibitor of SIRT1, a NAD+-dependent deacetylase. If NP220's function or interactions are affected by SIRT1 activity or its downstream targets, it could be indirectly modulated by this compound.