NMES1 Inhibitors
NMES1 inhibitors, also known as N-methyl-D-aspartate receptor subtype 1 inhibitors, belong to a class of chemical compounds that primarily target a specific type of receptor in the nervous system. These receptors, known as NMDA receptors, play a crucial role in the transmission of signals between nerve cells, known as neurons, in the brain and spinal cord. NMES1 inhibitors are designed to modulate the activity of these receptors by binding to them and altering their function.
The NMDA receptors are essential for various physiological processes, including learning and memory, as well as the perception of pain. NMES1 inhibitors typically act by blocking or reducing the activity of these receptors, which can have profound effects on neural communication. By doing so, they can influence synaptic plasticity, which is the ability of neurons to form new connections and adapt their function in response to experiences. This modulation of NMDA receptors can have far-reaching implications in the field of neuroscience and neuropharmacology
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is an isoflavone that can inhibit protein tyrosine kinases, potentially affecting signaling pathways NMES1 is associated with. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid, may inhibit phosphatidylinositol 3-kinases, which are involved in multiple signaling pathways, possibly influencing the activity of NMES1 indirectly. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a steroidal metabolite that irreversibly inhibits PI3K, which may indirectly affect NMES1 by altering signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a specific inhibitor of PI3K, which could affect NMES1's role in cellular signaling by altering the kinase activity in these pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor that may affect NMES1 by altering the MAPK/ERK pathway, which can influence numerous cellular functions. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is another MEK inhibitor that can influence the activity of NMES1 indirectly by modulating the MAPK/ERK signaling pathway. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Triciribine is an AKT inhibitor which may affect NMES1 indirectly by modulating the PI3K/AKT/mTOR pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor that may influence NMES1's role in stress response pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, which may affect signaling pathways related to NMES1's functions. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad-spectrum kinase inhibitor that can indirectly affect a wide range of cellular pathways, potentially including those involving NMES1. | ||||||