Date published: 2026-5-26

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NKCC1 Antibodies

Santa Cruz Biotechnology features a diverse variety of NKCC1 monoclonal antibodies for investigating Na-K-2Cl cotransporter 1 (NKCC1) in physiological processes. NKCC1 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). NKCC1 maintains cellular ion balance and regulates fluid homeostasis, with significant involvement in cell volume regulation and neuronal signaling. Research has shown that NKCC1 dysfunction can lead to various conditions, including hypertension, neurological disorders, and edema. Understanding NKCC1 function and regulation provides valuable insights into both normal physiology and disease development. Researchers can utilize specific NKCC1 monoclonal antibodies to examine expression patterns across different tissues and cellular compartments. Advanced imaging techniques combined with NKCC1 monoclonal antibodies enable detailed visualization of protein localization and trafficking. Extensive characterization of NKCC1 expression and activity continues to reveal new aspects of ion transport mechanisms. Santa Cruz Biotechnology monoclonal antibodies support the scientific community in advancing our understanding of NKCC1's role in health and disease states.

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NKCC1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

NKCC1 Antibody (A-6)

sc-514774mouse IgG2a κ886-1015 (h)WB, IP, IF, ELISAm, r, h
3
(3)

NKCC1 Antibody (F-4)

sc-514858mouse IgG2a κ78-99 (h)WB, IP, IF, IHC(P), ELISAh
2
(2)

NKCC1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NKCC1 CRISPR/Cas9 KO Plasmid (m)

sc-422971mGene KnockoutGFP0
(0)

NKCC1 HDR Plasmid (m)

sc-422971-HDRmHomology Directed RepairPuromycin0
(0)

NKCC1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NKCC1 CRISPR Activation Plasmid (m)

sc-422971-ACTmGene ActivationPuro, Blast, Hygro0
(0)

NKCC1 CRISPR Activation Plasmid (m2)

sc-422971-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

NKCC1 Lentiviral Activation Particles (m)

sc-422971-LACmGene ActivationPuro, Blast, Hygro0
(0)

NKCC1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NKCC1 siRNA (m)

sc-36072mGene SilencingN/A0
(0)

NKCC1 shRNA Plasmid (m)

sc-36072-SHmGene SilencingPuromycin0
(0)

NKCC1 shRNA (m) Lentiviral Particles

sc-36072-VmGene SilencingPuromycin0
(0)

NKCC1 siRNA (r)

sc-270468rGene SilencingN/A0
(0)

NKCC1 shRNA Plasmid (r)

sc-270468-SHrGene SilencingPuromycin0
(0)

NKCC1 shRNA (r) Lentiviral Particles

sc-270468-VrGene SilencingPuromycin0
(0)