Date published: 2026-3-20

1-800-457-3801

SCBT Portrait Logo
Seach Input

Nischarin Inhibitors

Nischarin inhibitors as a chemical class are defined by their ability to interact with and modulate signaling pathways that involve the Nischarin protein. These compounds typically target key signaling molecules or enzymes such as phosphoinositide 3-kinases (PI3K), mitogen-activated protein kinases (MAPKs), and mammalian target of rapamycin (mTOR), which are all upstream or downstream of where Nischarin functions. The inhibition of these signaling nodes can result in the alteration of cellular processes such as migration, proliferation, and adhesion that Nischarin is known to influence. The chemical structures of these compounds vary widely, from the macrolide structure of rapamycin to the small molecular inhibitors like LY294002, each designed to fit into the active sites of their target enzymes or signaling molecules. Given the role of Nischarin in various signaling pathways, the indirect inhibitors mentioned play a role in modulating the biological processes associated with Nischarin. These inhibitors are typically used in a research context to understand the complex signaling networks within the cell. The pathways targeted by these inhibitors, such as the PI3K/Akt pathway, MAPK pathway, and the mTOR signaling pathway, are integral to cell survival, proliferation, and differentiation. Inhibition of these pathways can lead to altered cell behavior which indirectly suggests the role Nischarin might play within these pathways. These chemicals are tools that provide insight into cellular signaling and are valuable in dissecting the intricate molecular interactions in which proteins like Nischarin participate.

SEE ALSO...

Items 1 to 10 of 14 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

BU 224 hydrochloride

187173-05-3sc-203857
sc-203857A
10 mg
50 mg
$119.00
$495.00
1
(0)

BU 224 hydrochloride functions as a nischarin, exhibiting selective binding to specific protein targets that modulate intracellular calcium levels. Its unique molecular architecture allows for the formation of hydrogen bonds, influencing conformational changes in target proteins. The compound's hydrophilic nature enhances its solubility in aqueous environments, promoting rapid distribution. Additionally, its kinetic profile reveals a propensity for reversible interactions, impacting its overall stability and reactivity in diverse chemical contexts.

KU14R

189224-48-4sc-204031
sc-204031A
10 mg
50 mg
$141.00
$599.00
2
(0)

KU14R acts as a nischarin, characterized by its ability to engage in specific non-covalent interactions with target biomolecules. Its unique structural features facilitate the formation of π-π stacking and hydrophobic interactions, which are crucial for its binding affinity. The compound demonstrates a distinctive reaction kinetics profile, exhibiting a rapid association and slower dissociation rate, thereby enhancing its effectiveness in modulating cellular pathways. Its amphiphilic nature contributes to its versatile behavior in various environments.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A potent inhibitor of PI3K, which is involved in the pathway that can affect Nischarin function related to cell migration and adhesion.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Another PI3K inhibitor that can modulate the PI3K/Akt signaling pathway, influencing processes where Nischarin is implicated.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

An inhibitor of MEK, which acts upstream of ERK in the MAPK pathway, indirectly affecting Nischarin-associated pathways.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

A selective inhibitor of MEK1/2, which can alter the MAPK/ERK pathway and consequently influence Nischarin′s role.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor that can regulate the PI3K/Akt/mTOR pathway, which is a potential regulator of Nischarin-mediated processes.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

A p38 MAPK inhibitor, can modulate the stress-activated MAPK pathway, affecting cellular functions associated with Nischarin.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

An inhibitor of JNK, which can impact the MAPK pathway, influencing cellular processes that involve Nischarin.

Gefitinib

184475-35-2sc-202166
sc-202166A
sc-202166B
sc-202166C
100 mg
250 mg
1 g
5 g
$63.00
$114.00
$218.00
$349.00
74
(2)

An EGFR inhibitor that can affect downstream signaling pathways involving Nischarin.