NHE-11 Activators
NHE-11 Activators belong to a specialized category of chemical compounds that have garnered attention in the field of molecular biology and cellular research. These activators are designed to modulate the activity of the NHE-11 gene, where NHE stands for Sodium-Hydrogen Exchanger, and NHE-11 denotes a specific isoform within this family. Sodium-hydrogen exchangers are integral membrane proteins that play a fundamental role in ion transport and cellular pH regulation. NHE-11 Activators represent a group of molecules engineered to enhance or stimulate the expression and function of the NHE-11 gene, ultimately leading to an increase in the activity of the associated protein.
The mechanism of action of NHE-11 Activators typically involves their interaction with specific regulatory elements within the NHE-11 gene, such as promoter regions or enhancer sequences. These interactions facilitate the upregulation of gene transcription, resulting in heightened synthesis of the NHE-11 protein. The NHE-11 protein is involved in the exchange of sodium and hydrogen ions across cell membranes, which can impact cellular pH and ion homeostasis. As researchers delve deeper into the functions and potential implications of NHE-11 activation, the development and refinement of NHE-11 Activators hold promise for advancing our understanding of ion transport mechanisms, cellular pH regulation, and the broader role of NHE-11 in cellular biology, potentially uncovering novel aspects of cellular homeostasis and ion dynamics.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
As a glucocorticoid, dexamethasone might influence NHE expression in cells as part of anti-inflammatory responses. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin might upregulate NHEs in certain tissues by promoting anabolic processes and altering cellular metabolism. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
By raising cAMP levels, forskolin could influence NHE expression through cAMP-dependent signaling pathways. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Involved in cell differentiation, retinoic acid might affect NHE expression in developing tissues or during cellular differentiation. | ||||||
Angiotensin II, Human | 4474-91-3 | sc-363643 sc-363643A sc-363643B sc-363643C | 1 mg 5 mg 25 mg 100 mg | $50.00 $75.00 $260.00 $505.00 | 3 | |
As a regulator of blood pressure and electrolyte balance, angiotensin II might modulate NHE expression in kidney and cardiovascular tissues. | ||||||
Aldosterone | 52-39-1 | sc-210774 sc-210774A sc-210774B sc-210774C sc-210774D sc-210774E | 2 mg 5 mg 10 mg 50 mg 100 mg 250 mg | $254.00 $209.00 $311.00 $1520.00 $3014.00 $7487.00 | 1 | |
This mineralocorticoid hormone could regulate NHE expression in the kidney as part of sodium and water homeostasis. | ||||||
Sodium bicarbonate | 144-55-8 | sc-203271 sc-203271A sc-203271B sc-203271C sc-203271D | 25 g 500 g 1 kg 5 kg 25 kg | $20.00 $28.00 $42.00 $82.00 $683.00 | 1 | |
As a buffer, bicarbonate might affect NHE expression by altering cellular pH homeostasis needs. | ||||||