Neu Inhibitors
Items 31 to 35 of 35 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
GW 583340 dihydrochloride | 388082-81-3 | sc-224012 sc-224012A | 1 mg 5 mg | $215.00 $850.00 | ||
GW 583340 dihydrochloride acts as a Neu through selective binding to active sites, where it stabilizes transient conformations of target enzymes. Its unique ability to form ionic interactions enhances its affinity, promoting effective substrate competition. The compound exhibits distinct reaction kinetics, characterized by rapid association and slower dissociation rates, which contribute to prolonged engagement with its molecular targets. Its solubility profile further influences its distribution and interaction dynamics in diverse environments. | ||||||
3-(4-Isopropylbenzylidenyl)indolin-2-one | 186611-55-2 | sc-202413 sc-202413A | 1 mg 5 mg | $39.00 $206.00 | ||
3-(4-Isopropylbenzylidenyl)indolin-2-one exhibits intriguing properties as a Neu, primarily through its capacity for π-π stacking interactions and hydrogen bonding with target biomolecules. This compound demonstrates unique reaction kinetics, marked by a notable lag phase before achieving equilibrium, suggesting complex conformational changes. Its lipophilic nature enhances membrane permeability, facilitating diverse molecular interactions and influencing its behavior in various biochemical pathways. | ||||||
Quinidine | 56-54-2 | sc-212614 | 10 g | $102.00 | 3 | |
Quinidine indirectly modulates neurotransmission by inhibiting voltage-gated sodium channels. By blocking sodium channels, Quinidine decreases the excitability of neurons, influencing action potential generation and the overall transmission of signals. While not specifically targeting a neurotransmitter, Quinidine's action on ion channels showcases the significance of ion channel modulation in shaping neuronal communication. | ||||||
GW2974 | 202272-68-2 | sc-252869 | 25 mg | $240.00 | ||
GW2974 showcases distinctive characteristics as a Neu, particularly through its ability to engage in specific molecular interactions, such as hydrophobic contacts and van der Waals forces. This compound exhibits a unique activation profile, characterized by rapid initial binding followed by slower dissociation rates, indicating potential allosteric modulation. Its structural rigidity contributes to enhanced selectivity in target engagement, influencing downstream signaling pathways and cellular responses. | ||||||
ErbB2 Inhibitor II | 928207-02-7 | sc-221592 | 5 mg | $284.00 | 2 | |
ErbB2 Inhibitor II demonstrates unique properties as a Neu by forming stable complexes with receptor tyrosine kinases, facilitating selective inhibition of dimerization. Its kinetic profile reveals a notable affinity for the ATP-binding site, leading to prolonged engagement and reduced turnover rates. The compound's conformational flexibility allows for tailored interactions with specific amino acid residues, modulating receptor activity and influencing cellular signaling cascades effectively. | ||||||