Molecular structure of ErbB2 Inhibitor II, CAS Number: 928207-02-7
ErbB2 Inhibitor II (CAS 928207-02-7)
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Application:
ErbB2 Inhibitor II is a chemical that reduces the phosphorylation of Neu (erbB2) but not erbB1
CAS Number:
928207-02-7
Purity:
≥95%
Molecular Weight:
262.3
Molecular Formula:
C15H10N4O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Cell-permeable triazole compound that targets the ATP-binding site of erbB2/HER2. Reduces the phosphorylation of erbB2 in MDA-MB-453 cells, but not that of the over-expressed erbB1 in MDA-MB-468 cells even at concentrations as high as 100 µM. Has been shown to suppress MDA-MB-453 growth with an IC50 of 30.9 µM.
Inhibitor of:
ErbB, and Neu.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ErbB2 Inhibitor II, 5 mg | sc-221592 | 5 mg | $290.00 |