Neu Inhibitors
Items 21 to 30 of 35 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BMS-599626 | 714971-09-2 | sc-364441 sc-364441A | 5 mg 25 mg | $255.00 $860.00 | ||
BMS-599626 functions as a Neu through its ability to selectively inhibit specific protein interactions, leveraging its unique structural features to modulate target enzyme conformations. The compound exhibits distinctive binding kinetics, characterized by a fast initial association followed by a slower dissociation phase, which fine-tunes its regulatory effects. Its hydrophobic regions enhance membrane permeability, facilitating interactions with lipid bilayers and influencing cellular signaling pathways. | ||||||
α-Methyl-L-p-tyrosine | 672-87-7 | sc-207232 | 25 mg | $260.00 | 1 | |
Alpha-methyltyrosine indirectly modulates neurotransmission by inhibiting tyrosine hydroxylase, a key enzyme in the synthesis of catecholamine neurotransmitters. By reducing the production of dopamine, norepinephrine, and epinephrine, Alpha-methyltyrosine impacts the signaling of catecholaminergic systems. | ||||||
TAK-285 | sc-364628 sc-364628A | 5 mg 10 mg | $405.00 $712.00 | |||
TAK-285 acts as a Neu by engaging in selective covalent modifications of target proteins, utilizing its electrophilic nature to form stable adducts. This compound demonstrates unique reactivity patterns, allowing it to preferentially interact with nucleophilic residues, thereby altering protein function. Its distinct steric properties promote specific conformational changes in target proteins, influencing downstream signaling cascades and cellular responses. The compound's solubility characteristics further enhance its distribution within biological systems. | ||||||
CP-724714 | 537705-08-1 | sc-364469 sc-364469A | 5 mg 10 mg | $180.00 $440.00 | ||
CP-724714 functions as a Neu through its ability to selectively inhibit specific kinases, disrupting critical signaling pathways. Its unique structural features facilitate strong binding interactions with ATP-binding sites, leading to a conformational shift in the target proteins. This compound exhibits a distinct kinetic profile, characterized by rapid association and slower dissociation rates, which enhances its efficacy in modulating cellular activities. Additionally, its hydrophobic characteristics influence membrane permeability and localization within cellular compartments. | ||||||
Hemicholinium-3 | 312-45-8 | sc-252873 sc-252873A | 100 mg 500 mg | $82.00 $405.00 | ||
Hemicholinium-3 indirectly inhibits neurotransmission by blocking the uptake of choline, a precursor for acetylcholine synthesis. Through the inhibition of choline uptake, Hemicholinium-3 disrupts acetylcholine production, impacting cholinergic neurotransmission. | ||||||
Arry-380 | 937265-83-3 | sc-364409 sc-364409A | 5 mg 10 mg | $435.00 $595.00 | ||
Arry-380 acts as a Neu by engaging in selective interactions with key protein targets, modulating their activity through unique conformational changes. Its distinct molecular architecture allows for specific binding to allosteric sites, influencing downstream signaling cascades. The compound exhibits a notable reaction kinetics profile, with a fast initial binding phase followed by a gradual stabilization, enhancing its regulatory effects. Furthermore, its lipophilic nature contributes to its distribution across cellular membranes, impacting its overall bioavailability. | ||||||
Canertinib | 267243-28-7 | sc-207397 | 10 mg | $260.00 | 3 | |
Canertinib functions as a Neu by selectively inhibiting receptor tyrosine kinases, disrupting critical phosphorylation events. Its unique structural features facilitate strong interactions with the ATP-binding pocket, leading to a conformational shift that alters receptor activity. The compound demonstrates a distinctive kinetic profile, characterized by a rapid association rate and prolonged dissociation, which enhances its efficacy in modulating signaling pathways. Additionally, its hydrophobic characteristics influence membrane permeability and cellular uptake. | ||||||
Hexamethonium chloride | 60-25-3 | sc-263383 | 5 g | $31.00 | ||
Hexamethonium indirectly influences neurotransmission by acting as a ganglionic blocker. By blocking nicotinic acetylcholine receptors in autonomic ganglia, Hexamethonium disrupts cholinergic neurotransmission in the autonomic nervous system. | ||||||
PD 158780 | 171179-06-9 | sc-358789 | 10 mg | $127.00 | 2 | |
PD 158780 acts as a Neu by targeting specific protein-protein interactions that stabilize the receptor's active conformation. Its unique binding affinity allows it to effectively compete with natural ligands, resulting in altered downstream signaling cascades. The compound exhibits a notable selectivity for certain isoforms, which influences its interaction dynamics. Furthermore, its lipophilic nature enhances its ability to penetrate cellular membranes, impacting its distribution within biological systems. | ||||||
Zanamivir sesquihydrate | 139110-80-8 (anhydrous) | sc-358987 sc-358987A | 5 mg 25 mg | $39.00 $128.00 | ||
Zanamivir sesquihydrate functions as a Neu by engaging in intricate hydrogen bonding and hydrophobic interactions with its target proteins, facilitating conformational changes that modulate enzymatic activity. Its structural rigidity contributes to a high degree of specificity, allowing it to effectively disrupt established molecular complexes. Additionally, the compound's solubility characteristics influence its diffusion rates, impacting its kinetic behavior in various environments. | ||||||