Hexamethonium chloride (CAS 60-25-3)
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Hexamethonium chloride is a chemical that functions as a ganglionic blocker in experimental applications. It acts by binding to nicotinic acetylcholine receptors on autonomic ganglia, thereby preventing the transmission of nerve impulses. This blockade of ganglionic transmission leads to a decrease in sympathetic and parasympathetic activity, resulting in a reduction of blood pressure and heart rate. At the molecular level, hexamethonium chloride competitively inhibits the binding of acetylcholine to its receptor, ultimately disrupting the normal physiological response to nerve stimulation. Hexamethonium Chloride′s mechanism of action involves interfering with the synaptic transmission between pre- and postganglionic neurons, effectively disrupting the autonomic nervous system′s control over various bodily functions. In experimental development, hexamethonium chloride′s mechanism of action is utilized to investigate the role of autonomic ganglia in regulating cardiovascular and other physiological processes.
Hexamethonium chloride (CAS 60-25-3) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hexamethonium chloride, 5 g | sc-263383 | 5 g | $31.00 |