Date published: 2025-11-30

1-800-457-3801

SCBT Portrait Logo
Seach Input

α-Methyl-L-p-tyrosine (CAS 672-87-7)

0.0(0)
Write a reviewAsk a question

See product citations (1)

Alternate Names:
L-2-Methyl-3-(4-hydroxyphenyl)alanine; L-AMPT
Application:
α-Methyl-L-p-tyrosine is a TH (tyrosine hydroxylase) inhibitor
CAS Number:
672-87-7
Molecular Weight:
195.2
Molecular Formula:
C10H13NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

α-Methyl-L-p-tyrosine is a compound of interest in biochemical research due to its role as a tyrosine hydroxylase inhibitor. It is used in studies to understand the biosynthesis of catecholamines, as it interferes with the conversion of tyrosine to L-DOPA, the precursor to dopamine, norepinephrine, and epinephrine. Research utilizing α-Methyl-L-p-tyrosine aims to dissect the pathways involved in catecholamine metabolism and to study the physiological consequences of altering these pathways. Furthermore, it serves as a tool to investigate the effects of reduced catecholamine synthesis on behavior and neurochemistry. It is also researched in the context of blood pressure and stress response.


α-Methyl-L-p-tyrosine (CAS 672-87-7) References

  1. Preparation and investigation of tumor affinity, uptake kinetic and transport mechanism of iodine-123-labelled amino acid derivatives in human pancreatic carcinoma and glioblastoma cells.  |  Samnick, S., et al. 2001. Nucl Med Biol. 28: 13-23. PMID: 11182560
  2. Dieldrin-induced oxidative stress and neurochemical changes contribute to apoptopic cell death in dopaminergic cells.  |  Kitazawa, M., et al. 2001. Free Radic Biol Med. 31: 1473-85. PMID: 11728820
  3. Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation.  |  Stegmaier, K., et al. 2004. Nat Genet. 36: 257-63. PMID: 14770183
  4. Mode of antinociceptive action of flupirtine in the rat.  |  Szelenyi, I., et al. 1989. Br J Pharmacol. 97: 835-42. PMID: 2569346
  5. Impaired distribution of alpha-methyl-L-p-tyrosine in diabetic rats.  |  Gbadebo, TD., et al. 1996. Brain Res. 739: 210-4. PMID: 8955941

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Methyl-L-p-tyrosine, 25 mg

sc-207232
25 mg
$260.00