NEDL2 Activators
NEDL2 (NEDD8 E3 ligase 2) is a protein-coding gene involved in ubiquitination, a cellular process responsible for regulating protein degradation and modulating various cellular activities, such as cell cycle progression, transcription, DNA repair, and apoptosis. NEDL2 is an E3 ubiquitin-protein ligase, meaning it plays a crucial role in recognizing and binding to specific substrate proteins destined for degradation or functional modification.
As an intricate part of the ubiquitin-proteasome system (UPS), NEDL2 is implicated in the maintenance of cellular homeostasis by controlling protein turnover. Its activity ensures that damaged or misfolded proteins are promptly tagged for degradation, thus blocking their accumulation, which could lead to cellular dysfunction. Additionally, by regulating the levels of various cellular proteins, NEDL2 can influence cell signaling pathways, possibly having a broader impact on cellular functions such as differentiation, proliferation, and stress responses. Understanding the precise roles and regulation of NEDL2 can provide insights into the molecular mechanisms underlying various physiological and pathological processes, potentially offering novel targets in conditions associated with protein misfolding or dysregulated protein degradation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
May regulate gene expression, potentially influencing NEDL2 transcription. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Could affect cellular stress responses, possibly influencing NEDL2 expression. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
As an oxidative agent, it might upregulate stress-related proteins like NEDL2. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $46.00 $92.00 $117.00 | 3 | |
May modulate cellular defense mechanisms, potentially influencing NEDL2 expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Could affect cAMP levels and thus potentially influence NEDL2 transcription. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc ions may play a role in protein stabilization, potentially affecting NEDL2 levels. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
May influence histone modification, potentially affecting NEDL2 transcription. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
As an antioxidant, it might modulate stress responses affecting NEDL2 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
May affect various cellular pathways, potentially influencing NEDL2 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Could modulate signaling pathways, potentially influencing NEDL2 transcription. | ||||||