Date published: 2026-5-15

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NCX Inhibitors

Santa Cruz Biotechnology now offers a broad range of NCX Inhibitors for use in various applications. Sodium-calcium exchangers (NCXs) are critical membrane transport proteins that play a vital role in maintaining intracellular calcium homeostasis by facilitating the exchange of intracellular calcium ions for extracellular sodium ions. This exchange is essential for the regulation of calcium levels within cells, which in turn controls various physiological processes, including muscle contraction, neuronal signaling, and cardiac rhythm. NCX Inhibitors are indispensable tools in scientific research, allowing researchers to study the function and regulation of these exchangers in different cellular contexts. By selectively inhibiting NCX activity, scientists can investigate the role of these exchangers in processes such as calcium signaling, electrical excitability, and cellular responses to stress. These inhibitors are widely utilized in research focused on understanding the pathophysiological mechanisms underlying conditions like cardiac arrhythmias, heart failure, and neurodegenerative diseases, where dysregulated calcium handling is a common feature. Additionally, NCX Inhibitors are valuable in the exploration of new therapeutic strategies aimed at modulating calcium dynamics in cells, potentially leading to the development of treatments for disorders associated with abnormal calcium exchange. The availability of these inhibitors has significantly advanced research in cardiovascular physiology, neurobiology, and cellular biochemistry, providing critical insights into the complex regulatory networks that govern calcium homeostasis and its impact on health and disease. View detailed information on our available NCX Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Bepridil hydrochloride

74764-40-2sc-202974
sc-202974A
10 mg
25 mg
$52.00
$104.00
2
(1)

Bepridil hydrochloride exhibits unique properties as a calcium-sodium exchanger (NCX), characterized by its ability to modulate ion transport across membranes. Its distinct molecular architecture facilitates specific binding interactions with ion channels, influencing the kinetics of ion exchange. The compound's hydrophilic and lipophilic regions contribute to its solubility profile, allowing for dynamic conformational changes that enhance its interaction with cellular membranes and impact ion homeostasis.

CGP 37157

75450-34-9sc-202097
sc-202097A
5 mg
25 mg
$115.00
$463.00
3
(1)

CGP 37157 functions as a sodium-calcium exchanger (NCX), distinguished by its selective affinity for calcium ions, which alters intracellular calcium levels. Its unique structural features enable it to engage in specific electrostatic interactions with membrane proteins, modulating ion flux. The compound's dynamic conformational flexibility enhances its ability to traverse lipid bilayers, influencing cellular signaling pathways and contributing to the regulation of calcium-dependent processes.