NALP11 Inhibitors
Regarding the chemical class of NALP11 inhibitors, the diverse nature of the chemicals reflects the complexity of indirectly targeting a protein like NALP11. These compounds primarily function by modulating various cellular pathways, such as inflammation, oxidative stress, and metabolic processes, which are intricately linked to the biological function of NALP11. The chemicals range from natural compounds like Resveratrol and Curcumin, known for their influence on inflammatory and stress pathways, to products like Ibuprofen and Metformin, which have broader effects on metabolic and inflammatory processes.
The indirect inhibition of NALP11 through these compounds demonstrates the interconnected nature of cellular signaling pathways. For instance, NSAIDs like Indomethacin and Ibuprofen, by modulating the inflammatory response, can influence the activity of NALP11 indirectly. Similarly, compounds like Epigallocatechin gallate and Quercetin, with their roles in modulating oxidative stress, can have downstream effects on proteins involved in related cellular responses, including NALP11. This indirect approach to inhibition showcases the complexity of targeting specific proteins within broader cellular contexts and highlights the potential of these compounds to influence NALP11 activity through their primary mechanisms of action on related pathways.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Interacts with multiple signaling pathways, including those involved in inflammation and cellular stress, potentially modulating NALP11 activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates inflammatory pathways, potentially influencing NALP11 activity by altering cellular responses to inflammation. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Modulates several signaling pathways, including those related to inflammation and oxidative stress, potentially influencing NALP11. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Influences inflammatory pathways and oxidative stress responses, potentially modulating NALP11 activity. | ||||||
Indomethacin | 53-86-1 | sc-200503 sc-200503A | 1 g 5 g | $28.00 $37.00 | 18 | |
A nonsteroidal anti-inflammatory drug that can influence pathways involving inflammation, potentially affecting NALP11. | ||||||
Ibuprofen | 15687-27-1 | sc-200534 sc-200534A | 1 g 5 g | $52.00 $86.00 | 6 | |
Another NSAID that modulates inflammatory pathways, potentially impacting NALP11 indirectly. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $41.00 | 4 | |
Modulates inflammatory and pain pathways, potentially influencing NALP11 activity. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Activates PPAR-gamma, a nuclear receptor that regulates gene expression involved in metabolism and inflammation, potentially affecting NALP11. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Influences metabolic pathways and has been shown to have effects on inflammatory processes, potentially impacting NALP11. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, influencing cellular growth and survival pathways, potentially impacting NALP11. | ||||||