N4BP2 Inhibitors
N4BP2 Inhibitors refers to a class of chemical compounds that specifically target and modulate the activity of Nedd4-binding protein 2 (N4BP2). N4BP2 is a multifunctional protein that plays a crucial role in various cellular processes, including signal transduction, protein degradation, and cellular homeostasis. Inhibitors within this chemical class are designed to interact with N4BP2, impeding its normal function or binding to other cellular components.
These inhibitors are characterized by their ability to disrupt the interactions involving N4BP2, potentially influencing downstream signaling pathways and cellular responses. The molecular structure of N4BP2 Inhibitors is intricately designed to fit the binding sites on N4BP2, thereby interfering with its interactions with target molecules. By doing so, these inhibitors may modulate cellular processes mediated by N4BP2, offering a valuable tool for researchers to dissect the intricate mechanisms of cellular signaling.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $68.00 $312.00 | 2 | |
Alsterpaullone is a cyclin-dependent kinase inhibitor that impedes cell cycle progression. By inhibiting these kinases, Alsterpaullone can negatively affect the phosphorylation state of proteins associated with the cell cycle, potentially restricting the activity of N4BP2 if it is involved in cell cycle regulation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a potent inhibitor of PI3K, a key enzyme in the PI3K/AKT/mTOR pathway. This pathway is involved in various cellular processes including metabolism, growth, and survival. Inhibition of this pathway by LY294002 could lead to downregulation of N4BP2 if it is a downstream effector of this signaling cascade. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is an inhibitor of MEK1/2, which are upstream activators of ERK1/2 in the MAPK/ERK pathway. Inhibition of this pathway could result in altered transcriptional regulation of genes including N4BP2 if it is regulated by MAPK/ERK signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAPK, a protein kinase involved in response to stress signals. By blocking p38 MAPK activity, SB203580 could impede the phosphorylation and activity of substrates that may include N4BP2 if it is implicated in the stress response. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor that can cause cell cycle arrest and autophagy. As mTOR is a central regulator of cell growth, rapamycin could decrease N4BP2 activity if N4BP2 is involved in mTOR signaling. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Bortezomib is a proteasome inhibitor. By preventing the degradation of ubiquitinated proteins, Bortezomib can lead to cellular stress and apoptosis. N4BP2 activity could be inhibited if it requires proteasome-mediated processing for its function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, which is involved in the regulation of apoptosis. By blocking JNK signaling, SP600125 could potentially decrease the activity of N4BP2, if it is associated with apoptosis signaling pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an inhibitor of MEK, which blocks the activation of MAPK/ERK. If N4BP2 is regulated by ERK signaling, its activity could be diminished by PD98059. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent inhibitor of phosphoinositide 3-kinases. By inhibiting PI3K, Wortmannin could downregulate N4BP2 if it is part of the PI3K/AKT signaling pathway. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
ZM447439 is an Aurora kinase inhibitor that can disrupt spindle formation and chromosome alignment during mitosis. If N4BP2 has a role in mitotic progression, ZM447439 could inhibit its function. | ||||||