Date published: 2026-5-30

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Myosin Ig Inhibitors

Myosin Ig Inhibitors, a distinctive class of chemical compounds, are substances designed to selectively target and modulate the activity of myosin Ig, a specific molecular motor protein within the myosin family. Myosins are crucial for a wide range of cellular processes, particularly those involving intracellular transport and muscle contraction. Myosin Ig, in particular, plays a pivotal role in the movement of intracellular vesicles and organelles along actin filaments, facilitating essential functions such as vesicle trafficking, cell division, and maintenance of cell structure.

The inhibitors within this chemical class are meticulously designed to interfere with the function of myosin Ig by binding to specific sites on the protein, disrupting its ability to interact with actin filaments effectively. This interference may lead to a variety of cellular consequences, including impaired vesicle transport, alterations in cell morphology, and disruptions in cellular signaling pathways. By specifically targeting myosin Ig, these inhibitors offer researchers a valuable tool for dissecting the intricate mechanisms of intracellular transport and cell motility. Furthermore, understanding the precise role of myosin Ig in cellular processes can shed light on its broader physiological significance and potential implications in various biological contexts. Researchers continue to explore the diverse applications and ramifications of Myosin Ig Inhibitors, unraveling the intricacies of cellular dynamics and expanding our knowledge of fundamental cellular biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(±)-Blebbistatin

674289-55-5sc-203532B
sc-203532
sc-203532A
sc-203532C
sc-203532D
5 mg
10 mg
25 mg
50 mg
100 mg
$183.00
$313.00
$464.00
$942.00
$1723.00
7
(1)

Inhibits myosin ATPase activity by binding to the motor domain, preventing actin-myosin interaction.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

Selective inhibitor of ROCK (Rho-associated protein kinase) that indirectly reduces myosin phosphorylation and contractility.

ML-7 hydrochloride

110448-33-4sc-200557
sc-200557A
10 mg
50 mg
$91.00
$267.00
13
(1)

Inhibits MLCK (Myosin Light Chain Kinase), preventing myosin light chain phosphorylation and contraction.

CK 666

442633-00-3sc-361151
sc-361151A
10 mg
50 mg
$321.00
$1040.00
5
(0)

Blocks actin filament polymerization, indirectly inhibiting myosin II interaction with actin.

SMIFH2

340316-62-3sc-507273
5 mg
$140.00
(0)

Disrupts actin cytoskeleton organization, leading to reduced myosin II contractility.

2,3-Butanedione 2-Monoxime

57-71-6sc-203774
sc-203774A
sc-203774B
sc-203774C
25 g
100 g
250 g
500 g
$42.00
$78.00
$161.00
$286.00
(1)

Blocks myosin ATPase activity, preventing actin-myosin interaction and muscle contraction.

Cytochalasin D

22144-77-0sc-201442
sc-201442A
1 mg
5 mg
$165.00
$486.00
64
(4)

Disrupts actin polymerization, indirectly affecting myosin II function in the cytoskeleton.

CK-869

388592-44-7sc-507274
5 mg
$163.00
(0)

CK-869 blocks actin polymerization and disrupts myosin interaction with actin filaments.