Myosin Ig Inhibitors, a distinctive class of chemical compounds, are substances designed to selectively target and modulate the activity of myosin Ig, a specific molecular motor protein within the myosin family. Myosins are crucial for a wide range of cellular processes, particularly those involving intracellular transport and muscle contraction. Myosin Ig, in particular, plays a pivotal role in the movement of intracellular vesicles and organelles along actin filaments, facilitating essential functions such as vesicle trafficking, cell division, and maintenance of cell structure.
The inhibitors within this chemical class are meticulously designed to interfere with the function of myosin Ig by binding to specific sites on the protein, disrupting its ability to interact with actin filaments effectively. This interference may lead to a variety of cellular consequences, including impaired vesicle transport, alterations in cell morphology, and disruptions in cellular signaling pathways. By specifically targeting myosin Ig, these inhibitors offer researchers a valuable tool for dissecting the intricate mechanisms of intracellular transport and cell motility. Furthermore, understanding the precise role of myosin Ig in cellular processes can shed light on its broader physiological significance and potential implications in various biological contexts. Researchers continue to explore the diverse applications and ramifications of Myosin Ig Inhibitors, unraveling the intricacies of cellular dynamics and expanding our knowledge of fundamental cellular biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Inhibits myosin ATPase activity by binding to the motor domain, preventing actin-myosin interaction. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Selective inhibitor of ROCK (Rho-associated protein kinase) that indirectly reduces myosin phosphorylation and contractility. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Inhibits MLCK (Myosin Light Chain Kinase), preventing myosin light chain phosphorylation and contraction. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $321.00 $1040.00 | 5 | |
Blocks actin filament polymerization, indirectly inhibiting myosin II interaction with actin. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
Disrupts actin cytoskeleton organization, leading to reduced myosin II contractility. | ||||||
2,3-Butanedione 2-Monoxime | 57-71-6 | sc-203774 sc-203774A sc-203774B sc-203774C | 25 g 100 g 250 g 500 g | $42.00 $78.00 $161.00 $286.00 | ||
Blocks myosin ATPase activity, preventing actin-myosin interaction and muscle contraction. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Disrupts actin polymerization, indirectly affecting myosin II function in the cytoskeleton. | ||||||
CK-869 | 388592-44-7 | sc-507274 | 5 mg | $163.00 | ||
CK-869 blocks actin polymerization and disrupts myosin interaction with actin filaments. | ||||||