MYH8 Activators
Common MYH8 Activators include, but are not limited to Retinoic Acid, all trans CAS 302-79-4, Dexamethasone CAS 50-02-2, Forskolin CAS 66575-29-9, GW501516 CAS 317318-70-0 and AICAR CAS 2627-69-2.
MYH8 is a member of the myosin superfamily, a group of proteins that play a central role in cellular motility processes, especially those linked with actin filaments. Myosins are not just integral to muscle contraction but also significantly influence a plethora of cellular activities such as organelle transportation, maintenance of cell shape, and vesicle transportation. Each myosin subtype has been tailored through evolution to possess a particular domain structure and function, rendering it suited to its specific cellular role. MYH8, distinguished by its unique domain configuration and tissue localization, is involved in specialized cellular functions that are distinct from its myosin counterparts.
Activators of MYH8 are designed to enhance or stimulate the activity of the MYH8 protein. These molecules can amplify the protein's function by either increasing its affinity for actin, enhancing its ATPase activity, or promoting its structural conformational changes that are essential for function. The increased activity of MYH8 induced by these activators can, in turn, amplify the cellular processes in which MYH8 is involved. Researching MYH8 activators can shed light on the nuances of its function within the cell, revealing the intricacies of its contribution to cellular motility and structure. Moreover, these compounds offer a unique lens to view the broader workings of the myosin superfamily, emphasizing the delicate balance and interactions between its various members.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid plays a role in cell differentiation. It might stimulate muscle cell differentiation and potentially upregulate MYH8 expression in certain contexts. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone can promote muscle differentiation in vitro. It could potentially induce MYH8 expression during muscle cell maturation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels in cells. This can influence various cellular pathways, including those in muscle cells, possibly inducing MYH8 expression. | ||||||
GW501516 | 317318-70-0 | sc-202642 sc-202642A | 1 mg 5 mg | $82.00 $179.00 | 28 | |
Known as a PPARδ agonist, GW501516 promotes fat burning. Its effects on muscle metabolism might indirectly influence MYH8 expression. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR affects energy metabolism and can influence muscle function. It might indirectly influence the expression of muscle-specific genes like MYH8. | ||||||
L-3,3′,5-Triiodothyronine, free acid | 6893-02-3 | sc-204035 sc-204035A sc-204035B | 10 mg 100 mg 250 mg | $41.00 $77.00 $153.00 | ||
Thyroid hormones like T3 play roles in muscle development and function. They might influence the expression of muscle-specific proteins, including MYH8. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 plays roles in calcium homeostasis and might influence muscle function. It could potentially affect the expression of muscle-related genes, including MYH8. | ||||||