MUP20 Inhibitors
MUP20 inhibitors are a class of chemical compounds that specifically target Major Urinary Protein 20 (MUP20), a member of the MUP family involved in pheromone binding and release in rodent species. MUP20, like other MUP proteins, plays a key role in the storage and transport of volatile pheromones. These proteins are secreted in the urine and bind to small, hydrophobic molecules, which can then be released gradually into the environment, influencing social interactions, mate selection, and territorial behavior. By inhibiting MUP20, researchers can block the binding of pheromones to the protein, disrupting the normal chemical signaling processes that mediate these behaviors.
In scientific studies, MUP20 inhibitors are valuable tools for dissecting the molecular mechanisms behind pheromone signaling and its behavioral effects. By preventing MUP20 from binding its ligands, researchers can explore how the inhibition of this specific protein affects pheromone detection and social dynamics in animal models. These inhibitors provide insight into the structural dynamics of MUP20, helping to elucidate the precise molecular interactions involved in ligand binding and release. Additionally, MUP20 inhibitors enable the study of how blocking pheromone-related signaling pathways influences behavior, allowing scientists to better understand the role of MUPs in regulating communication and behavior within rodent populations. These inhibitors serve as important molecular probes for understanding the function and significance of MUP20 in natural biological systems.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $246.00 $490.00 $536.00 | 16 | |
Inhibits JAK/STAT signaling, crucial for Mup20 expression. Suppresses neural precursor cell proliferation and olfactory learning, indirectly inhibiting Mup20 activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Targets the ERK/MAPK pathway, essential for positive regulation of neurogenesis. Inhibits neurogenesis-related cellular processes associated with Mup20, acting as an indirect inhibitor by disrupting ERK/MAPK signaling. | ||||||
PD 169316 | 152121-53-4 | sc-204168 sc-204168A sc-204168B sc-204168C | 1 mg 5 mg 10 mg 25 mg | $86.00 $153.00 $275.00 $452.00 | 3 | |
Selective inhibitor of p38 MAPK, impacting Mup20-related pathways. Modulates cellular processes involved in positive regulation of neural precursor cell proliferation, serving as an indirect inhibitor by influencing p38 MAPK signaling. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K/AKT pathway, crucial for Mup20-related processes. Disrupts positive regulation of neurogenesis, serving as an indirect inhibitor through the modulation of PI3K/AKT signaling. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Irreversible PI3K inhibitor affecting Mup20 expression. Impedes positive regulation of neural precursor cell proliferation and olfactory learning, acting as an indirect inhibitor through PI3K pathway disruption. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor disrupting Mup20-related pathways. Modulates cellular processes involved in positive regulation of neurogenesis, serving as an indirect inhibitor through the suppression of JNK signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor affecting the ERK/MAPK pathway associated with Mup20. Disrupts positive regulation of neurogenesis, acting as an indirect inhibitor through the inhibition of MEK/ERK signaling. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor impacting Mup20-related processes. Modulates cellular processes involved in positive regulation of neural precursor cell proliferation, serving as an indirect inhibitor through the suppression of mTOR signaling. | ||||||
D-erythro-Sphingosine | 123-78-4 | sc-3546 sc-3546A sc-3546B sc-3546C sc-3546D sc-3546E | 10 mg 25 mg 100 mg 1 g 5 g 10 g | $88.00 $190.00 $500.00 $2400.00 $9200.00 $15000.00 | 2 | |
Inhibits NF-κB, a key player in Mup20-related pathways. Modulates cellular processes involved in positive regulation of neurogenesis, serving as an indirect inhibitor through the suppression of NF-κB signaling. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
TGF-β receptor inhibitor disrupting Mup20-associated pathways. Modulates cellular processes involved in positive regulation of neural precursor cell proliferation, serving as an indirect inhibitor through the suppression of TGF-β signaling. | ||||||