MSLNL Activators

The MSLNL gene is located on chromosome 16 and is composed of 7 exons. Its protein product, MSLNL, shares a significant sequence similarity with mesothelin, particularly in the C-terminal region. However, unlike mesothelin, it lacks an N-terminal region that is known to bind to CA125/MUC16, a protein that is often elevated in ovarian cancer.While the expression pattern and physiological role of MSLNL are not well-documented, it's speculated that this protein may play a role in cellular adhesion, similar to mesothelin. It's also possible that MSLNL could be involved in other cellular processes due to its potential as a membrane-anchored protein.

Given the link between mesothelin and various cancers, it's conceivable that MSLNL might also have implications in oncology. However, the lack of substantial research into this protein makes it difficult to draw any firm conclusions.In summary, MSLNL is a protein that shares sequence similarity with mesothelin. Its exact function and implications in disease remain largely unknown. It represents an interesting target for further research, particularly considering the known role of mesothelin in certain types of cancer.