Date published: 2026-4-13

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MRTF Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of MRTF Antibodies for investigating myocardin-related transcription factors (MRTFs) in cellular processes. MRTF Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MRTFs are essential regulators of gene expression involved in smooth muscle differentiation, cell migration, and response to mechanical stress. Research has shown that MRTFs play a significant role in cardiovascular development and influence various pathological conditions, including fibrosis and cancer. Understanding MRTF function provides valuable insights into cellular signaling pathways and potential therapeutic targets. Ongoing studies continue to reveal new aspects of MRTF biology and their impact on cellular processes. Advanced research techniques and methodologies help uncover the molecular mechanisms through which MRTFs regulate gene expression. Current investigations focus on how MRTFs respond to different cellular stimuli and environmental conditions. Santa Cruz Biotechnology monoclonal antibodies for MRTF research support scientists in advancing our understanding of these important transcription factors and their role in human health and disease.

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MRTF Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MRTF-A/MKL1 Antibody (G-7)

sc-398675mouse IgM κ905-931 (h)WB, IP, IF, ELISAm, r, h
18
(10)

MRTF-A/MKL1 Antibody (G-8)

sc-390324mouse IgG2a κ761-900 (h)WB, IP, IF, ELISAm, r, h
25
(6)

MRTF CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MRTF-B CRISPR/Cas9 KO Plasmid (h)

sc-401793hGene KnockoutGFP0
(0)

MRTF-B HDR Plasmid (h)

sc-401793-HDRhHomology Directed RepairPuromycin0
(0)

MRTF-A/MKL1 CRISPR/Cas9 KO Plasmid (h)

sc-400338hGene KnockoutGFP0
(0)

MRTF-A/MKL1 HDR Plasmid (h)

sc-400338-HDRhHomology Directed RepairPuromycin0
(0)

MRTF-A/MKL1 CRISPR/Cas9 KO Plasmid (m)

sc-432390mGene KnockoutGFP0
(0)

MRTF-A/MKL1 HDR Plasmid (m)

sc-432390-HDRmHomology Directed RepairPuromycin0
(0)

MRTF CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MRTF-B CRISPR Activation Plasmid (h)

sc-401793-ACThGene ActivationPuro, Blast, Hygro0
(0)

MRTF siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MRTF-B siRNA (h)

sc-61074hGene SilencingN/A
2
(0)

MRTF-B shRNA Plasmid (h)

sc-61074-SHhGene SilencingPuromycin
2
(0)

MRTF-B shRNA (h) Lentiviral Particles

sc-61074-VhGene SilencingPuromycin
2
(0)

MRTF-B siRNA (m)

sc-61075mGene SilencingN/A0
(0)

MRTF-B shRNA Plasmid (m)

sc-61075-SHmGene SilencingPuromycin0
(0)

MRTF-B shRNA (m) Lentiviral Particles

sc-61075-VmGene SilencingPuromycin0
(0)

MRTF-A/MKL1 siRNA (h)

sc-43944hGene SilencingN/A
5
(1)

MRTF-A/MKL1 shRNA Plasmid (h)

sc-43944-SHhGene SilencingPuromycin
5
(1)

MRTF-A/MKL1 shRNA (h) Lentiviral Particles

sc-43944-VhGene SilencingPuromycin
5
(1)

MRTF-A/MKL1 siRNA (m)

sc-149641mGene SilencingN/A0
(0)

MRTF-A/MKL1 shRNA Plasmid (m)

sc-149641-SHmGene SilencingPuromycin0
(0)

MRTF-A/MKL1 shRNA (m) Lentiviral Particles

sc-149641-VmGene SilencingPuromycin0
(0)