MRP-L13, also known as mitochondrial ribosomal protein L13, is a component of the large subunit (39S) of the mitochondrial ribosome in humans. The protein is encoded by the MRPL13 gene and is integral to mitochondrial protein synthesis, which is crucial for the production of proteins that are essential for the mitochondrial electron transport chain and oxidative phosphorylation.
Mitochondrial ribosomes are distinct from their cytoplasmic counterparts and are specialized for the synthesis of a subset of proteins encoded by the mitochondrial genome. These proteins are typically embedded in the inner mitochondrial membrane and are involved in vital metabolic processes, such as ATP production through oxidative phosphorylation. MRP-L13 contributes to the proper assembly and function of the mitochondrial ribosome, ensuring the precision and efficiency of mitochondrial translation.In addition to its role in protein synthesis, MRP-L13 and other mitochondrial ribosomal proteins have been implicated in various cellular processes including apoptosis, cellular growth, and the response to metabolic stress. Abnormalities in mitochondrial ribosomal proteins can lead to defects in mitochondrial function, which are associated with a range of human diseases, including mitochondrial disorders, neurodegenerative diseases, and the aging process.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $284.00 | ||
A derivative of Coenzyme Q10, targeting mitochondria and potentially enhancing mitochondrial function, indirectly affecting MRPL13. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Known to improve mitochondrial function and could indirectly influence MRPL13 activity as part of the mitochondrial protein synthesis machinery. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
A coenzyme in redox reactions, crucial for mitochondrial function, potentially impacting MRPL13 indirectly. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
An anti-diabetic drug that improves mitochondrial function, which could indirectly affect MRPL13. | ||||||
Elamipretide | 736992-21-5 | sc-507453 | 25 mg | $670.00 | ||
Targets mitochondrial dysfunction, potentially influencing mitochondrial ribosome function and indirectly MRPL13. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, known to affect mitochondrial function and may have indirect effects on MRPL13. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
Used for dyslipidemia; known to enhance mitochondrial function, potentially affecting MRPL13. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A component of green tea, shown to influence mitochondrial function, possibly impacting MRPL13. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
A key component in the mitochondrial electron transport chain, possibly affecting MRPL13 activity indirectly. | ||||||
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $238.00 | ||
Influences mitochondrial biogenesis, potentially affecting MRPL13. | ||||||