Date published: 2026-4-12

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MLKL Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of MLKL monoclonal antibodies for research focused on understanding cell death and inflammation mechanisms. MLKL monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Mixed lineage kinase domain-like protein (MLKL) plays a crucial role in necroptosis, a form of programmed cell death that is distinct from apoptosis. By mediating the cellular response to stress and inflammation, MLKL is essential for maintaining tissue homeostasis and regulating immune responses. Understanding MLKL function is vital for elucidating its involvement in various diseases, including neurodegenerative disorders and cancer. Researchers studying MLKL can explore its role in cell signaling pathways and inflammatory responses. MLKL research continues to reveal new insights into disease mechanisms and potential therapeutic targets. Current investigations focus on how MLKL influences cell death decisions and inflammatory signaling cascades. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of MLKL's role in health and disease.

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MLKL Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MLKL Antibody (3B2)

sc-293201mouse IgG2a κ371-471 (h)WB, IP, IF, IHC(P), FCM, ELISAh
15
(5)

MLKL CRISPR Knockout, HDR and Double Nickase Plasmids

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MLKL CRISPR/Cas9 KO Plasmid (h2)

sc-401248-KO-2hGene KnockoutGFP0
(0)

MLKL HDR Plasmid (h2)

sc-401248-HDR-2hHomology Directed RepairPuromycin0
(0)

MLKL Double Nickase Plasmid (h)

sc-401248-NIChGene KnockoutPuromycin0
(0)

MLKL Double Nickase Plasmid (h2)

sc-401248-NIC-2hGene KnockoutPuromycin0
(0)

MLKL CRISPR/Cas9 KO Plasmid (m)

sc-428931mGene KnockoutGFP0
(0)

MLKL HDR Plasmid (m)

sc-428931-HDRmHomology Directed RepairPuromycin0
(0)

MLKL Double Nickase Plasmid (m)

sc-428931-NICmGene KnockoutPuromycin0
(0)

MLKL Double Nickase Plasmid (m2)

sc-428931-NIC-2mGene KnockoutPuromycin0
(0)

MLKL CRISPR Activation Products

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MLKL CRISPR Activation Plasmid (h)

sc-401248-ACThGene ActivationPuro, Blast, Hygro0
(0)

MLKL CRISPR Activation Plasmid (h2)

sc-401248-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MLKL siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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MLKL siRNA (h)

sc-93430hGene SilencingN/A
5
(0)

MLKL shRNA Plasmid (h)

sc-93430-SHhGene SilencingPuromycin
5
(0)

MLKL shRNA (h) Lentiviral Particles

sc-93430-VhGene SilencingPuromycin
5
(0)

MLKL siRNA (m)

sc-149468mGene SilencingN/A
2
(0)

MLKL shRNA Plasmid (m)

sc-149468-SHmGene SilencingPuromycin
2
(0)

MLKL shRNA (m) Lentiviral Particles

sc-149468-VmGene SilencingPuromycin
2
(0)