Date published: 2026-9-9

1-800-457-3801

SCBT Portrait Logo
Seach Input

MIP-2 Inhibitors

MIP-2 inhibitors encompass a diverse range of molecules and compounds that have been developed and explored for their potential to modulate the activity of Macrophage Inflammatory Protein-2 (MIP-2), also known as CXCL2. MIP-2 is a chemokine involved in orchestrating the migration and activation of neutrophils, a type of immune cell, during inflammatory processes. MIP-2 Inhibitors are meticulously designed to interact with MIP-2 or its associated receptors, aiming to interfere with the signaling pathways that trigger neutrophil recruitment and activation. By targeting MIP-2, these inhibitors offer a means to investigate and manipulate the complex mechanisms that govern immune cell trafficking and inflammation-related responses. The study of MIP-2 Inhibitors contributes to advancing our understanding of immune system dynamics, shedding light on the molecular intricacies that guide immune cell movement and function. Ongoing research endeavors continue to unravel the mechanisms of action and broader implications associated with MIP-2 Inhibitors, thereby enhancing our insights into the fundamental principles that underlie immune responses and contribute to the body's defense mechanisms.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

SB 225002

182498-32-4sc-202803
sc-202803A
1 mg
5 mg
$36.00
$102.00
2
(1)

A selective antagonist of the CXCR2 receptor, which is a primary receptor for MIP-2, thus inhibiting MIP-2-mediated signaling.

Reparixin

266359-83-5sc-507446
5 mg
$78.00
(0)

This compound inhibits the binding of MIP-2 to the CXCR2 receptor, thereby potentially attenuating neutrophil recruitment.

PF-3644022

1276121-88-0sc-478487
sc-478487A
5 mg
25 mg
$367.00
$2856.00
(0)

This inhibitor also targets the CXCR2 receptor and has been explored for its potential to modulate neutrophil migration mediated by MIP-2.

YM 254890

568580-02-9sc-507356
1 mg
$510.00
(0)

Originally identified as a Gαq/11 inhibitor, YM254890 has been found to inhibit MIP-2-induced neutrophil chemotaxis.