mGluR-8a Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(2S,4R)-gamma-Hydroxyglutamic acid | 2485-33-8 | sc-283521 sc-283521A | 10 mg 50 mg | $196.00 $568.00 | ||
(2S,4R)-gamma-Hydroxyglutamic acid acts as a selective modulator of mGluR-8a, exhibiting unique stereochemical properties that enhance its binding affinity. Its hydroxyl group facilitates specific interactions with receptor sites, promoting distinct conformational changes. This compound's ability to stabilize receptor dimers may influence signal transduction efficiency, while its kinetic profile suggests a rapid onset of action, potentially affecting synaptic plasticity and neurotransmitter release dynamics. | ||||||
(RS)-PPG | 120667-15-4 | sc-202797 | 5 mg | $71.00 | ||
(RS)-PPG functions as a modulator of mGluR-8a, characterized by its unique structural features that promote selective receptor engagement. Its chiral centers contribute to specific stereoelectronic interactions, enhancing binding precision. The compound's dynamic conformational flexibility allows it to navigate various receptor states, potentially influencing downstream signaling pathways. Additionally, its interaction kinetics suggest a nuanced role in receptor desensitization and recovery, impacting overall neuronal communication. | ||||||
(S)-3,4-DCPG | 201730-11-2 | sc-204255 sc-204255A | 10 mg 50 mg | $202.00 $833.00 | ||
(S)-3,4-DCPG acts as a selective modulator of mGluR-8a, distinguished by its ability to stabilize receptor conformations through specific hydrogen bonding and hydrophobic interactions. Its stereochemistry facilitates precise alignment within the binding pocket, enhancing affinity and selectivity. The compound exhibits unique reaction kinetics, allowing for rapid onset and offset of action, which may influence synaptic plasticity and neuronal signaling dynamics. Its distinct molecular interactions contribute to a finely tuned regulatory role in glutamatergic transmission. | ||||||
NPEC-caged-(S)-3,4-DCPG | sc-359017 sc-359017A | 10 mg 50 mg | $275.00 $1163.00 | |||
NPEC-caged-(S)-3,4-DCPG serves as a potent modulator of mGluR-8a, characterized by its unique caging mechanism that enables controlled release upon photolysis. This compound exhibits distinct molecular flexibility, allowing it to adopt various conformations that optimize binding interactions. Its ability to engage in specific electrostatic interactions enhances receptor activation, while its kinetic profile supports precise temporal control over signaling pathways, influencing neuronal communication and synaptic efficacy. | ||||||